نتایج جستجو برای: dehalogenase and non dehalogenases

تعداد نتایج: 17006963  

Journal: :Biochemistry 2002
Aaron J Oakley Zbynek Prokop Michal Bohác Jan Kmunícek Tomás Jedlicka Marta Monincová Ivana Kutá-Smatanová Yuji Nagata Jirí Damborský Matthew C J Wilce

The hydrolysis of haloalkanes to their corresponding alcohols and inorganic halides is catalyzed by alpha/beta-hydrolases called haloalkane dehalogenases. The study of haloalkane dehalogenases is vital for the development of these enzymes if they are to be utilized for bioremediation of organohalide-contaminated industrial waste. We report the kinetic and structural analysis of the haloalkane d...

Journal: :Applied and environmental microbiology 2005
Alison S Waller Rosa Krajmalnik-Brown Frank E Löffler Elizabeth A Edwards

Degenerate primers were used to amplify 14 distinct reductive-dehalogenase-homologous (RDH) genes from the Dehalococcoides-containing mixed culture KB1. Most of the corresponding predicted proteins were highly similar (97 to >99% amino acid identity) to previously reported Dehalococcoides reductive dehalogenases. To examine the differential transcription of these RDH genes, KB1 was split into f...

Journal: :Science 2005
Rekha Seshadri Lorenz Adrian Derrick E Fouts Jonathan A Eisen Adam M Phillippy Barbara A Methe Naomi L Ward William C Nelson Robert T Deboy Hoda M Khouri James F Kolonay Robert J Dodson Sean C Daugherty Lauren M Brinkac Steven A Sullivan Ramana Madupu Karen E Nelson Katherine H Kang Marjorie Impraim Kevin Tran Jeffrey M Robinson Heather A Forberger Claire M Fraser Stephen H Zinder John F Heidelberg

Dehalococcoides ethenogenes is the only bacterium known to reductively dechlorinate the groundwater pollutants, tetrachloroethene (PCE) and trichloroethene, to ethene. Its 1,469,720-base pair chromosome contains large dynamic duplicated regions and integrated elements. Genes encoding 17 putative reductive dehalogenases, nearly all of which were adjacent to genes for transcription regulators, an...

Journal: :Journal of structural biology 2007
Martina Pavlová Martin Klvana Andrea Jesenská Zbynek Prokop Hana Konecná Takashi Sato Masataka Tsuda Yuji Nagata Jirí Damborský

Haloalkane dehalogenase DhmA from Mycobacterium avium N85 showed poor expression and low stability when produced in Escherichia coli. Here, we present expression DhmA in newly constructed pK4RP rhodococcal expression system in a soluble and stable form. Site-directed mutagenesis was used for the identification of a catalytic pentad, which makes up the reaction machinery of all currently known h...

Journal: :Acta crystallographica. Section F, Structural biology and crystallization communications 2008
Alena Stsiapanava Tana Koudelakova Mikalai Lapkouski Martina Pavlova Jiri Damborsky Ivana Kuta Smatanova

The enzyme DhaA from Rhodococcus rhodochrous NCIMB 13064 belongs to the haloalkane dehalogenases, which catalyze the hydrolysis of haloalkanes to the corresponding alcohols. The haloalkane dehalogenase DhaA and its variants can be used to detoxify the industrial pollutant 1,2,3-trichloropropane (TCP). Three mutants named DhaA04, DhaA14 and DhaA15 were constructed in order to study the importanc...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه اصفهان - دانشکده زبانهای خارجی 1389

abstract the current study sets out 1) to investigate the strategic needs of iranian efl learners in reading literary and non-literary texts; 2) to shed some light on the differences between reading literary and non-literary texts; and 3) to specify the differences in the interaction of participants with texts while reading two literary subgenres ( i.e., short story and literary essays). to ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی - دانشکده ادبیات و زبانهای خارجی 1391

although there are studies on pragmatic assessment, to date, literature has been almost silent about native and non-native english raters’ criteria for the assessment of efl learners’ pragmatic performance. focusing on this topic, this study pursued four purposes. the first one was to find criteria for rating the speech acts of apology and refusal in l2 by native and non-native english teachers...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه ولی عصر (عج) - رفسنجان - دانشکده ادبیات و علوم انسانی 1393

the present study investigated construct equivalence of multiple choice (mc) and constructed response (cr) item types across stem and content equivalent mc and cr items (item type ‘a’), non-stem-equivalent but content equivalent mc and cr items (item type ‘b’), and non-stem and non-content equivalent mc and cr items (item type ‘c’). one hundred seventy english-major undergraduates completed mc ...

Journal: :Applied and environmental microbiology 2016
Jacob E Munro Elissa F Liew Mai-Anh Ly Nicholas V Coleman

UNLABELLED 1,2-Dichloroethane (DCA) is a problematic xenobiotic groundwater pollutant. Bacteria are capable of biodegrading DCA, but the evolution of such bacteria is not well understood. In particular, the mechanisms by which bacteria acquire the key dehalogenase genes dhlA and dhlB have not been well defined. In this study, the genomic context of dhlA and dhlB was determined in three aerobic ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم انسانی 1392

this research has been taken among the students of high school in karaj city during the years 1391 and 1392. this is a survey research and data gathering is through questionnaires. studying the “an analysis of students’ tendency toward non-native reference groups in karaj”. the questionnaire was distributed among 260 of these students who were chosen through multi step cluster sampling. conside...

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