نتایج جستجو برای: deflazacort
تعداد نتایج: 144 فیلتر نتایج به سال:
Background: Duchenne muscular dystrophy (DMD) is a severe progressive inherited neuromuscular disorder, caused by mutations in DMD gene. Although onset of disease can be observed during the first age live, most patients exhibit signs muscle weakness between 3 to 5 years and around 10-12 individuals loss ambulation (LoA). Standard care treatment include use steroids. The two commonly prescribed ...
Deflazacort (DFZ) is an oxazoline derivative of prednisolone with anti-inflammatory and immunosuppressive activity. The aim of this study was to investigate and to identify the main degradation product of DFZ, and to evaluate the anti-inflammatory effect of both DFZ and its major degradation product (namely DDP1). DFZ was subjected to alkaline and acid degradation. In 0.1 N NaOH, DFZ was immedi...
improvement in nasal symptoms (congestion and hydrorrhea, and, to a lesser extent, hyposmia); 2 months later she had also achieved better asthma control (no further need for rescue bronchodilator use and no asthma symptoms, leading to the withdrawal of inhaled corticosteroids and long-acting ß 2 agonists, and a signifi cant improvement of FEV 1 up to 90% of predicted). After 16 weeks of treatme...
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