Introduction There is no doubt that, since the invention of artificial joint replacement, many thousands of people have enjoyed freedom from disabling pain and immobility. However, this remarkable success story is marred by the incidence of local sepsis following surgery, which can lead to prosthesis loosening and the need for revision surgery. In fact, deep wound infections are the most seriou...

We report on a 20-year-old female high-school student with fulminant meningococcal sepsis presenting as severe skin necrosis in lower extremities. The wound surface affected 2% of her total body surface area and was covered with black eschar. The adipose tissue beneath the eschar was degenerated and turned to necrosis as to deep fascia and periosteum of lower tibia. Excision of necrotic eschar,...

SUMMA RY: A case of dental sepsis is presented which resulted in a deep neck infection and enntually caused a mediastinal abscess. The microbiology of such a mixed infection is briefly discussed with emphasis on the synergistic activity of tht! organisms. The anatomy of the fascial spaces is also described to draw attention 10 the possible routes of spread of this potentially life threatening c...

introduction:guillain-barre syndrome(gbs) is the most common cause of acute flaccid paralysis. respiratory failure is the most serious short-term complication of gbs and invasive mechanical ventilation is required in 30% of patients.moreover,60% of those who are intubated develop major complications including pnemonia,sepsis,gi bleeding and pulmonary embolism. thus respiratory failure predictio...

Background: Neonatal sepsis is a generalized bacterial infection which occurs in the first month of life. Intraventricular hemorrhage is the most common intracerebral disorder which occurs in premature neonates. Mean Platelet Volume (MPV) is considered as a marker of intraventricular hemorrhage (IVH) in some studies. The aim of this study was to evaluate the impact of MPV on IVH and sepsis in n...

A5.2 year-old Holstein cow was presented with lameness andabnormal weight bearing in a slaughterhouse. Widening of theperiople and swelling of the heel area in the lateral claw was morepermanent than the medial claw. Vertical fissure (VF) involvingthe coronary band to the middle of the dorsal wall of the medialhind claw was observed. It was also extended to the bearingsurface in the inner surfa...

OBJECTIVE To report on the clinical presentation and possible risk factors leading to hand sepsis, amputation, management, and outcome in diabetic patients presenting to a multidisciplinary diabetic center in Khartoum, Sudan. METHODS This is a retrospective descriptive study of all diabetic patients presenting with hand sepsis between September 2002 and March 2008 to Jabir Abueliz Diabetic Ce...

Sepsis associated encephalopathy (SAE) is a common but poorly understood neurological complication of sepsis. It is characterized by diffuse brain dysfunction secondary to infection elsewhere in the body without overt CNS infection. The pathophysiology of SAE is complex and multifactorial including a number of intertwined mechanisms such as vascular damage, endothelial activation, breakdown of ...

The burden of thromboembolism (TE) in severe sepsis is largely unknown. We assessed the prevalence of venous and arterial TE in patients with severe sepsis over a four-week period. We performed a retrospective analysis of a pooled database of three randomized, placebo-controlled trials of two novel pharmacological agents for the treatment of severe sepsis, drotrecogin alfa (activated) (DrotAA) ...

background: multiple severity scoring systems have been devised and evaluated in adult sepsis, but a simplified scoring model for pediatric sepsis has not yet been developed. this study aimed to develop and validate a new scoring model to stratify the severity of pediatric sepsis, thus assisting the treatment of sepsis in children. methods: data from 634 consecutive patients who presented with ...