introduction: this study is aimed to compare phenotypic test methods and determine antibiotic susceptibility pattern of ampc beta-lactamase producing uropathogenic escherichia coli and klebsiella pneumoniae in clinical isolates. method: e. coli and k. pneumoniae were identified by standard microbiological procedures. screening of ampc beta-lactamase production was done by using cefoxitin disc (...

BACKGROUND AND OBJECTIVE AmpC β lactamases are one of the important causes of drug resistance in gram negative bacteria. Failure to detect these enzymes in the laboratory has contributed to therapeutic failures but there are till date no standard guideline available. This study was therefore undertaken to evaluate three phenotypic laboratory tests and the inhibitors used in two of the tests to ...

A comparative study on the reliability of toxicokinetic parameters for predicting hepatotoxicity was conducted in male F344 rats receiving a single (106 mg/kg by gavage) or 7-day repeated (1000 ppm in feed, 97 mg/kg/day) administration of p,p'-DDT. DDT was selected as the test substance because it is known as a hepatotoxic agent and its metabolic pathway is well documented. Concentrations of DD...

DNA-damage tolerance (DDT) is defined as a mechanism by which eukaryotic cells resume DNA synthesis to fill the single-stranded DNA gaps left by replication-blocking lesions. Eukaryotic cells employ two different means of DDT, namely translesion DNA synthesis (TLS) and template switching, both of which are coordinately regulated through sequential ubiquitination of PCNA at the K164 residue. In ...

Following an episode of star formation, Type Ia supernova events occur over an extended period of time, following a distribution of delay times (DDT). We critically discuss some empirically-based DDT functions that have been proposed in recent years, some favoring very early (prompt) events, other very late (tardy) ones, and therefore being mutually exclusive. We point out that in both cases th...

BACKGROUND & OBJECTIVES Kala-azar or visceral leishmanisis (VL) is known to be endemic in several States of India including West Bengal (WB). Only meager information is available on the vector dynamics of its vector species, Phlebotomus argentipes particularly in relation to control measure from this State. Hence, a pilot study was undertaken to assess the control strategy and its impact on vec...

BACKGROUND Older adults with cerebrovascular accident (CVA) show evidence of auditory and speech perception problems. In present study, it was examined whether these problems are due to impairments of concurrent auditory segregation procedure which is the basic level of auditory scene analysis and auditory organization in auditory scenes with competing sounds. METHODS Concurrent auditory segr...

BACKGROUND Antimicrobial resistance in hospital pathogens is an important concern. It can cause longer hospital stays, increase costs, and contribute to increased mortality and morbidity in hospitalized patients. The aim of this study was to categorize and identify gram-negative bacilli capable of ESBLs production and to study the effect of MIC silver nanoparticles on bacteria strains and then ...

INTRODUCTION AND OBJECTIVE Hearing disorders among school-age children are a current concern. Continuing studies have been performed in Poland since 2008, and on 2 December 2011 the EU Council adopted Conclusions on the Early Detection and Treatment of Communication Disorders in Children, Including the Use of e-Health Tools and innovative Solutions. The discussion now focuses not only on the ef...

BACKGROUND There is mounting evidence that deteriorated semen quality may be associated with increased serum concentration of 1,1,1-trichloro-2,2-bis(chlorodiphenyl)ethane (DDT) and its metabolites. The problem is exacerbated in situations where DDT is the only resource available to control malaria mosquitoes and DDT metabolite plasma concentration can reach 1000-fold the level found in other p...