The circadian rhythmicity of hormone secretion, body temperature, and sleep/wakefulness results from an endogenous rhythm of neural activity generated by clock genes in the suprachiasmatic nucleus (SCN). One of these genes, Clock, has been considered essential for the generation of cellular rhythmicity centrally and in the periphery; however, melatonin-proficient Clock(Delta19) + MEL mutant mic...

black leg has been reported in a variety of animals, but is ofthe most importance in cattle and sheep. a20 days old holsteindairy calf was examined because of anorexia and lameness from2 days ago. the calf was depressed, tachypneic, tachycardic, andhad a body temperature of 38.5ºc. both hind limbs proximal tothe tarsal joint were markedly swollen, firm and painful. nocrepitation was noted on pa...

The adaptation of a slow (soleus, Sol) and a fast (medial gastrocnemius, MG) skeletal muscle to spaceflight was studied in five young male rats. The flight period was 12.5 days and the rats were killed approximately 48 h after returning to 1 g. Five other rats that were housed in cages similar to those used by the flight rats were maintained at 1 g for the same period of time to serve as ground...

Black leg has been reported in a variety of animals, but is ofthe most importance in cattle and sheep. A20 days old Holsteindairy calf was examined because of anorexia and lameness from2 days ago. The calf was depressed, tachypneic, tachycardic, andhad a body temperature of 38.5ºC. Both hind limbs proximal tothe tarsal joint were markedly swollen, firm and painful. Nocrepitation was noted on pa...

We present a simplified and fast method for simulating minor mergers between galaxy clusters. Instead of following the evolution of the dark matter halos directly by the N-body method, we employ a rigid potential approximation for both clusters. The simulations are run in the rest frame of the more massive cluster and account for the resulting inertial accelerations in an optimised way. We test...

objective(s): pregabalin (pgb) is a new antiepileptic drug that has received fda approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. this study was undertaken to evaluate the possible adverse effects of pgb on the muscular system of mice. materials and methods: to evaluate the effect of pgb on skeletal...

A method is described which measures the excitation of Agriolimax by light, during the progress of light adaptation, by assuming that the orientating effect of continuous excitation is expressed as a directly proportionate tension difference in the orienting muscles of the two sides of the body. The tendency toward establishment of such a tension difference is caused to work against a similar g...