cadmium has been known to be harmful to human health, mainly via contaminated drinking water, food supplies, tobacco and industrial pollutants. the aim of this study was to determine the ability of cadmium chloride (cdcl 2 ) to cause cell death in the human lung carcinoma cell line (calu-6). the cells were grown in rpmi-1640 medium supplemented with 10% fcs, penicillin/streptomycin (100 u/ml, 1...

Background: Berberine and Nano-curcumin are two herbal medicines with strong anti-cancer effects on tumor cells, but low toxicity on normal cells, when used alone. Breast cancer is known as the most common cancer in women and second deadly one. In this study, we evaluated the cytotoxicity effects of combination Berberine and Nano-curcumin in breast cancer cell line to see whether they have furt...

application of nanotechnology in medicinal and biological fields has attracted a great interest in the recent yeras. in this paper the cell membrane leakage induced by iron nanoparticles (fe-np) against pc12 cell line which is known as a model of nervous system cell line was investigated by the lactate dehydrogenase (ldh) test. therefore, pc12 cells were incubated with different concentration o...

objective(s) malva sylvestris l. (malvaceae), an annual plant, has been already commonly used as a medicinal plant in iran. in the present work, we evaluate some bioactivities of the plant extracts. materials and methods the aired-dried plant flowers and leaves were extracted by soxhlet apparatus with n-hexane, dichloromethane and methanol. the antimicrobial, cytotoxic, and phytotoxic of the pl...

loxosceles rufescens , commonly known as the mediterranean recluse or mediterranean fiddle-back spider is recorded from iran for the first time. the genus loxosceles contains 103 accepted species, two of them (including l. rufescens ) are cosmopolitan. all loxosceles species tested so far possess necrotic venoms, which is a unique characteristic among the order araneae. considering this charact...

background: a strong antimicrobial synergism between chlorhexidine (chx) and hydrogen peroxide (h2o2) has been reported, but there is not enough data on the cytotoxicity of this combination. the primary aim of this study was to evaluate the cytotoxicity of chx-h2o2 combination in different concentrations and secondary aim is to assess the infl uence of h2o2 on cytotoxicity of chx on cultured hu...

objective: resin cements, regardless of their biocompatibility, have been widely used in restorative dentistry during the recent years. these cements contain hydroxy ethyl methacrylate (hema) molecules which are claimed to penetrate into dentinal tubules and may affect dental pulp. since tooth preparation for metal ceramic restorations involves a large surface of the tooth, cytotoxicity of thes...

results in vitro analysis showed that the greater the concentration of the extract, the greater the cytotoxicity. conclusions the crude extract of p. australis might be cytotoxic at high concentrations as evaluated against the cell line. materials and methods the mtt cytotoxicity assay was performed on a 3t3 mouse fibroblast cell line to measure the in vitro cytotoxic activity of the crude form...

background: despite the wide range of applications, there is a serious lack of information on the impact of the nanoparticles on human health and the environment. the present study was done to determine the range of dangerous concentrations of iron oxide nanoparticle and their effects on mouse embryonic stem cells. methods: iron oxide nanoparticles with less than 20 nanometers diameter were enc...

objective: the number of new cancer cases with considerable mortality is increasing worldwide. since the inability of current therapies in treatment of patients and prevention the progress of tumors with fewer side effects, implementation of new methods is needed. gene therapy has widespread systemic cytotoxic effects against tumor cells. rotavirus nsp4 has been shown to elicit extensive cytoto...