BACKGROUND It is well known that cytomegalovirus esophagitis occurs in immunosuppressed patients. However, few reports have described cytomegalovirus esophagitis occurring during chemoradiotherapy for esophageal cancer. CASE PRESENTATION We report two cases of patients with cytomegalovirus esophagitis that developed during chemoradiotherapy for esophageal cancer. Cytomegalovirus esophagitis w...

BACKGROUND Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection. CASE PRESENTATION Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months. CONCLUSION Even if the molecular identity betw...

The clearance of cytomegalovirus viraemia in HIV-1-infected patients may partly result from the inhibition of cytomegalovirus protease by HIV-1 protease inhibitors contained in highly active antiretroviral therapy. We used a computational method to calculate the binding affinity of six HIV-1 protease inhibitors to cytomegalovirus protease based on its X-ray crystallography structure. The calcul...

recently, using polymerase chain reaction (pcr) technique, the dna of cytomegalovirus was detected from depigmented white patches in patients with vitiligo. the reactivation of infection and occasional anti-cmv igm circulating among patients infected by cytomegalovirus has been reported for years. we have studied 26 patients with clinical signs and symptoms of vitiligo, some of whom had a histo...

stevens-johnson syndrome (sjs) and toxic epidermal necrolysis (ten) are severe adverse cutaneous reactions to drugs. we describe the case of a 19 year old patient with sjs/ten overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. a cytomegalovirus infection was diagnosed by real time polymerase chain reaction (rt-pcr) detection on bronchoalveo...

Human cytomegalovirus utilizes cellular signal transduction pathways to activate viral or cellular transcription factors involved in the control of viral gene expression and DNA replication. In the present study, we demonstrate that Harvey-ras-transformed cells show increased permissiveness to human cytomegalovirus when compared to their parental non-transformed cells. Both the progeny viral yi...

Purpose: A bidirectional interaction between cytomegalovirus and hepatitis C is hypothesized to adversely affect the outcome of liver transplantation for chronic hepatitis C. This article reviews the clinical data on this hepatitis C virus-cytomegalovirus interaction. Methods: Review of (i) studies that assessed the impact of cytomegalovirus on hepatitis C virus viremia, recurrent hepatitis C, ...

background and objective: cytomegalovirus (cmv) infections are associated with severe morbidity and mortality in patients, especially pediatric renal transplantation patients. the use of immunosuppressive agents places these patients at the risk of viral infections. as cytomegalovirus infection influences the graft outcome, adopting useful strategies for limiting this virus after transplantatio...

The typical radiographical findings of cytomegalovirus pneumonitis are bilateral interstitial infiltrates. In this study, the current authors describe two patients on corticosteroid treatment for systemic lupus erythematosus, complicated by histologically confirmed cytomegalovirus pneumonitis, presenting as cavitary masses. This rare presentation of cytomegalovirus pneumonitis broadens the diff...

Congenital cytomegalovirus infection is a major cause of central nervous system and sensory impairments that affect cognition, motor function, hearing, language development, vestibular function, and vision. Although the importance of congenital cytomegalovirus infection is readily evident, the vast majority of maternal and fetal infections are not identified, even in developed countries. Multip...