OBJECTIVES Congenital cytomegalovirus (CMV) infection is one of the most common intrauterine diseases. In all, 1% of live births is affected by cytomegalovirus infection, while 90% neonates with perinatal infection do not show symptoms of disease. Symptomatic CMV is present in 5-10% of children. Typical clinical signs of CMV infection are microcephalia, mental retardation, progressive major amb...

The presence of Herpes Simplex Virus-type 2 (HSV type 2), Cytomegalovirus(CMV) and Adenovirus lgG antibodies was determined in sera from a total 144 patients with hematologic solid organ malignancies. HSV type-2 were detected using the EIA method antibody levels 34(48.5 %) ofthe 56(75.6 malignancies of90 (62.5 %). Anti-CMV IgG same serum samples complement fixation test. Residual anti-CMV 43(61...

CMV: cytomegalovirus DIHS: drug-induced hypersensitivity syndrome DRESS: drug reaction with eosinophilia and systemic symptoms HHV: human herpesvirus WBC: white blood cell INTRODUCTION Drug-induced hypersensitivity syndrome (DIHS)/ drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse systemic reaction. DIHS is characterized by its limited number of causative drugs, ...

Cytomegalovirus (CMV) retinitis is one of the rare but debilitating presentations of the CMV infection in children with leukemia. Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. The definite diagnosis of CMV retinitis was made after vitreous aspiration. Despite prompt treatment and ophthalmologic interventi...

T HE FOUR PROBLEMS that still limit the overall success of allogeneic bone marrow transplantation (BMT) are regimen-related toxicity, recurrent leukemia, graft-versus-host disease (GVHD), and cytomegalovirus (CMV) infection. The last 5 years have seen considerable progress in improving the treatment and prevention of GVHD and decreasing leukemic relapse.' Until recently, cytomegalovirus was a m...

Background & Aims: Maternal infections with parvovirus B19 and cytomegalovirus (CMV) maybe associated with intrauterine fetal death. The aim of this study was to compare frequency of CMV & Parvovirus B19 Infections in intrauterine fetal death (IUFD) and normal pregnancy. Methods: In a case-control study in Afzalipour Hospital during 2006 placental biopsies were collected from 70 cases of IUFD a...

Cytomegalovirus (CMV) infection is one of the most common infections that affects humans’ cardiovascular system. Although the literature includes controversial evidence for any correlation between CMV infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. However, the number of prospective...

survival such as GVHD and leukemia risk group. Elmaagacli and colleagues propose several explanations for these results (see figure). First, myeloid cells are a reservoir for CMV. It is possible that viral reactivation in AML blasts makes them a target for subsequent attack by virus-specific cytotoxic T cells (CTLs). Alternatively, CMV reactivation in AML cells may up-regulate leukocyte fixatio...

Background: Cytomegalovirus (CMV) is a ubiquitous virus and has significant implications in the immune suppressed. Several cases of CMV colitis have been reported in neonates, acquiring the virus in a variety of ways, through vertical transmission, breast milk, or blood transfusion. Case Presentation: Here we report a full-term infant who developed severe cytomegalovirus colitis post-operativel...

Cytomegalovirus (CMV) infection in immunocompetent adults is usually asymptomatic, but results lifelong latency. Infection occurring congenitally or immunodeficiency can lead to cognitive impairment. We aimed investigate the associations between CMV exposure and intelligence quotient (IQ) patients with schizophrenia spectrum disorders (SZS), bipolar (BDS) healthy controls (HC). immunoglobulin G...