chronic inflammation is associated with the development of various diseases such as atherosclerosis and diabetes. the aim of this study was to investigate the effect of 8 weeks of resistance training on changes of c reactive protein (crp) and cystatin c in male volleyball players. for this purpose, 20 volleyball players voluntarily participated in the study and were divided randomly into progre...

OBJECTIVE Studies have shown that both cystatin C and metabolic syndrome (MetS) are associated with inflammation. We set out to investigate the correlation between serum cystatin C levels and MetS in the elderly. METHODS This prospective study was conducted in 380 elderly individuals, including 135 patients with MetS, 142 patients with metabolic disturbance (MetD), and 103 healthy elderly ind...

Cystatin C is one of a family of proteinase inhibitors of cathepsins and other cysteine proteinases. Among warm-blooded vertebrates, small functional regions of cystatin amino acid sequences are well conserved among species, but major portions of cystatin amino acid sequences vary evolutionarily. Although considerable attention has been given to mammalian and avian cystatins, little data exist ...

INTRODUCTION Estimation of the glomerular filtration rate (GFR) is essential for the evaluation of patients with kidney disease, and for treating patients with drugs that are eliminated from the circulation by the kidneys. Cystatin C has been shown to be superior to creatinine for estimating GFR in several studies. However, studies showing that thyroid function has an impact on cystatin C have ...

BACKGROUND Cystatin C-based equations are used to estimate GFR. However, three cystatin C immunoassays are on the market. Difference in cystatin C assays could have strong consequences on the accuracy and precision of cystatin C-based equations. We have performed an analytical study of these three assays and studied potential differences between assays on the precision of cystatin C-based equat...

OBJECTIVE The purpose of this study was to determine the levels of Cystatin C in healthy term newborns in the first month of life. INTRODUCTION Cystatin C may be a suitable marker for determining the glomerular filtration rate because it is not affected by maternal renal function. METHODS Cohort study. Inclusion: term newborns with appropriate weight; mother without renal failure or drugs t...

BACKGROUND/AIMS The relationship between carotid artery plaque burden, phenotype and serum cystatin C at normal and impaired renal function is still unclear. METHODS Demographic characteristics, carotid ultrasonography and other relevant information of 1,477 patients were collected. The association of carotid artery plaque burden, plaque phenotype with serum cystatin C was evaluated by strate...

INTRODUCTION Measurement of glomerular filtration rate (GFR) is critical for the diagnosis and stratification of chronic kidney disease (CKD). Recent studies have shown that cystatin C is superior to creatinine for the detection of impaired GFR, and several cystatin C-based equations for estimating GFR have been developed for this clinical application. We conducted the present study to assess t...

Trophoblast invasion is regulated by proteinases and their inhibitors. Cystatin C inhibits cysteine proteinases. The serum concentration of cystatin C is increased in late pregnancy and pre-eclampsia. We aimed to investigate whether the expression of cystatin C is increased in the pre-eclamptic placenta and to investigate the expression pattern of cystatin C mRNA and protein in placental tissue...

BACKGROUND Cystatin C is reportedly a better endogenous marker of glomerular filtration rate than serum creatinine, so the prognostic value of cystatin C in patients with ST-elevation myocardial infarction (MI) was evaluated in the present study. METHODS AND RESULTS A total of 71 patients who underwent percutaneous coronary intervention for ST-segment elevation MI <24 h from symptom onset wer...