A new diarylheptanoid containing a chalcone moiety, katsumain H (1), was isolated from the seeds of Alpinia katsumadai. The structure was elucidated using a combination of 1D/2D NMR spectroscopy and mass spectrometry data analysis. The absolute configurations of C-3, C-5, and C-7 in 1 were assigned based on its optical rotation and after comparing its NMR chemical shifts with those of its diast...

in this study, a researching program is conducted by cyclic triaxial test to determine the post-cyclic behavior of bushehr carbonate sand retrieved from the north of the persian gulf, under anisotropic consolidation at 200 kpa confining pressure. the article compares the post-cyclic monotonic strength and excess pore water pressures generated after the test with the pre-cyclic monotonic results...

abstract: this paper presents the results of pullout tests on uniaxial geogrid embedded in silica sand under monotonic and cyclic pullout forces. the new testing device as a recently developed automated pullout test device for soil-geogrid strength and deformation behavior investigation is capable of applying load/displacement controlled monotonic/cyclic forces at different rates/frequencies an...

In a previous works searching for new drugs with high efficiency, we reported the in vitro and in vivo antileishmanial activity of a series of diarylheptanoid structurally related to curcumin against L. amazonensis. This work describes the in vitro antileishmanial activity of a new series of diarylheptanoids and diarylpentanoids derivatives. These drugs were assayed against Leishmania amazonens...

Naturally occurring diarylheptanoid curcumin (CUR), a principal component of the Asian spice turmeric, has been shown to have anti-cancer effects in many tumor types. However, a detailed mechanism regarding CUR induced tumor cell killing remain to be comprehensively explored. Using two head neck squamous cell carcinoma (HNSCC) cell lines FaDu (hypopharyngeal) and Cal27 (tongue), we demonstrated...

this paper presents the results of a series of monotonic and post-cyclic triaxial tests carried out on a clay specimen and three types of clay-sand mixed specimens. the focus of the paper is on the post-cyclic mechanical behavior of the mixed specimens, as compared to their monotonic behavior. analyses of the tests results show that cyclic loading degrade undrained shear strength and deformatio...