our previous studies showed that the promyelocytic leukemia protein, pml, functions as acellular and growth suppressor. transient expression of pml was also found to repress the activity of theepidermal growth factor receptor (egfr) gene promoter. in this study, we have examined the effects ofpml on a431 cells, which express a high level of egfr protein. the pml gene was introduced into thecell...

the vertex arboricity $rho(g)$ of a graph $g$ is the minimum number of subsets into which the vertex set $v(g)$ can be partitioned so that each subset induces an acyclic graph‎. ‎a graph $g$ is called list vertex $k$-arborable if for any set $l(v)$ of cardinality at least $k$ at each vertex $v$ of $g$‎, ‎one can choose a color for each $v$ from its list $l(v)$ so that the subgraph induced by ev...

one of the basic tenets in recent international trade literature is about the effect of trade integration on business cycle synchronization (bcs) among trading countries. the objective of this paper is to explore the main determinants of business cycle synchronization, with emphasis on trade integration. to this end, we have specified two simultaneous regression equations which were estimated b...

cancer treatment is still of the greatest challenges that health care providers and patients are facing. one of the unsolved problems in cancer treatment is cells’ reaction to metabolic stress caused by harsh nutritional conditions around tumor. in order to be able to treat this disease properly, it is important to understand the true nature of the disease. in fact, the cells inside the central...

black seed (nigella sativa) is considered as a biological response modifier. thymoquinone (tq) is the bioactive and the most abundant constituent of the volatile oil of this seed which has been shown to possess anti-inflammatory, antioxidant and anti-neoplastic effects. in this study, the effect of tq on hepg2 cell line was investigated in an attempt to identify its potential mechanism of actio...

the transcriptional factor sox2 regulates the expression of some of the developmental genes, which are essential for the maintenance of pluripotency of stem cells. sox2 also expresses in the female gamete during folliculogenesis, but its role remains ambiguous. the aim of this study was to investigate the expression of sox2 in the mice ovarian tissue during different stage of estrous cycle. adu...

abstract background: the intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient. objective: the aim of this study was to identify independent factors which could be used to identify total fertilization failure before the day of intracytoplasmic sperm injection. materials and methods: this was a retrosp...

a special class of cubic graphs are the cycle permutation graphs. a cycle permutation graph pn(α) is defined by taking two vertex-disjoint cycles on n vertices and adding a matching between the vertices of the two cycles.in this paper we determine a good upper bound for tenacity of cycle permutation graphs.

introduction: estrogen and progesterone are supposed to modify pain sensitivity. however, the actual role of each of these steroid hormones in this respect is not well known. plasma concentrations of these hormones show variation during estrous cycle. the role of alpha2 receptors in tonic pain has been pointed out. the aim of the present study was to investigate the agonist and antagonist effec...