BACKGROUND Chemotherapy still relies on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosin, and allopurinol. In this study, we explained about the native plant that grows in different regions of Iran and used as anti-leishmanial in Iran and even many other countries. METHODS This narrative review covers all information about local herbal medicine in Iran that used in ...

Canine leishmaniosis is a widely spread zoonosis that is potentially fatal to humans and dogs. Infection with Leishmania infantum is considerably more prevalent than clinical disease, and infected dogs with no signs of disease might, potentially, transmit infection. Diagnosis of asymptomatic infection by serology is insufficient and PCR markedly increases its sensitivity. A new therapy exclusiv...

A method for the evaluation of splenic cellularity using samples collected by fine-needle aspirative biopsy was standardized in this work. The procedure includes erythrocyte lysing, preparation of cytospin films and staining by histochemical and immunocytochemical techniques. The cellular profiles of spleen preparations were compared with those observed in peripheral blood samples subjected to ...

Introduction: Infectious diseases remain a major public health problem in developing countries. The objective of this study was to determine the epidemiological and clinical profile infectious pathology department CHU Yalgado Ouédraogo Ouagadougou. Patients method: This cross-sectional retrospective that took place University Hospital from January 1, 2019 December 31, 2019. Were included all pa...

The increasing awareness that control of zoonotic visceral leishmaniosis (ZVL) depends on effective control of canine leishmaniosis has promoted research into leishmanial infection in dogs, but has also encouraged the indiscriminate elimination of seropositive dogs. Public health campaigns in various parts of the world (e.g. in Brazil and China) are designed to reduce the incidence of human ZVL...

Cellular immune response to Leishmania plays a key role in canine leishmaniosis. However, there are few assays to evaluate this response in the dog. Here, we evaluated and compared three assays of specific cellular immune response to Leishmania infantum in dogs: the leishmanin skin test (LST), lymphocyte proliferation assay (LPA) and IFN-gamma cytopathic effect inhibition bioassay (IFNB). Fifty...