conclusions a higher number of bacterial flora was found in the bodybuilders particularly those using aas in comparison to the controls, which might be due to the influence of these aas on the skin microflora and transmission of the bacteria through the direct contact of the naked skin with the exercise instruments. background anabolic-androgenic steroids (aas) abuse by the athletes has dramati...

Background Drug reaction with eosinophilia and systemic symptom (DRESS) is a severe drug-induced cutaneous reaction with visceral involvement and blood abnormalities associated with reactivations of herpes-virus family i.e., EBV, HHV-6, HHV-7 and CMV. Recently, we demonstrated that the immune response in DRESS, previously thought to be directed only against drug components, is also mediated by ...

Background In Steven Johnson’s syndrome (SJS) and Toxic epidermal necrolysis (TEN), Chung et al. demonstrated that granulysin is the key cytotoxic molecule. But the specificity of granulysin in SJS-TEN is actually discussed. We studied the granulysin expression of 6 types of cutaneous adverse drug reaction (CADR) with a proven diagnosis (maculopapular exanthema (MPE), Drug Reaction with Eosinop...

Adverse drug reactions are a major hazard of modern medicine. Fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Here we report 37-year-old female with bullous fixed drug eruptions due to doxycycline administration.

Cutaneous drug reactions have a variety of clinical presentations. This review focuses on the most common or severe cutaneous reaction patterns. Knowledge of the clinical morphology and the most commonly associated medication aids in rapid diagnosis and institution of the appropriate therapy.

conclusions torghabeh - shandiz district with a rural texture is endemic for anthroponotic cutaneous leishmaniasis (acl). further studies are recommended to discover the vectors and probable reservoirs in these areas. results of 164 samples obtained from the skin lesions of the patients referred to the torghabe - shandiz health centers, leishmania dna was isolated from 136 smears by pcr method....

Fixed drug eruptions (FDE) are the common dermatological adverse drug reaction accounts for 16-21% of all cutaneous drug reactions in India. Drugs most frequently implicated in FDE are antimicrobials, anticonvulsants, and nonsteroidal antiinflammatory drugs. Here, we report a rare case of bullous FDE due to ciprofloxacin followed by ofloxacin administration.

Background: DRESS syndrome is a distinctive, severe, and atypical drug reaction includes rash with eosinophilia organ dysfunction symptoms, as well hematological abnormalities. This disease diagnosed using the Regis CAR (European Registry of Severe Cutaneous Adverse Reaction) scoring system. Case presentation: A 25-year-old lady presented complaints skin lesion over whole body since 3 days alon...