concurrent infection with Torulopsis glabrata in a dog. Predisposing factors included a history of chronic skin disease of obscure origin treated with antibiotics and/or corticosteroids for 6 months. Laboratory findings, sebaceous gland atrophy, epidermal atrophy, and epidermal hyperkeratosis were all findings that were consistent with those of corticosteroid effects. The immune status of this ...

The Hallermann-Streiff syndrome is a complex association of developmental anomalies principally involving structures of ectodermal origin. The constant expressions of the syndrome are dyscephaly with mandibulo-facial malformation, bilateral congenital cataracts, and dental anomalies, while hypotrichosis, cutaneous atrophy, microphthalmos, and proportionate dwarfism are frequently present (Table...

Progressive facial hemiatrophy (PFH) is a rare condition characterized by the slow, progressive appearance of a unilateral facial atrophy that affects the skin, subcutaneous tissue, muscle and bone. We report the case of a 60-year-old female patient whose cutaneous symptoms commenced in 1987 in the form of a purplish erythema on the left side of her face and neck, which subsequently remitted gi...

OBJECTIVE To report clinical features, response to treatment, and long-term follow-up of nail lichen planus in children. DESIGN Retrospective study involving 15 children with nail lichen planus. SETTING Outpatient consultation for nail disorders at the Department of Dermatology of the University of Bologna, Bologna, Italy. PATIENTS OR OTHER PARTICIPANTS We diagnosed nail lichen planus in ...

Cutaneous atrophy arising from prolonged use of potent topical corticosteroids has long been a concern. Thus, it would be advantageous to find an agent which protects against atrophy produced by corticosteroids but at the same time does not impair their anti-inflammatory effects. Recent work shows that topical all-trans retinoic acid (tretinoin) prevents skin atrophy in mice treated with topica...

A 1-year-old, female, domestic shorthair cat was referred for orthopaedic evaluation of acute-onset, non-progressive left pelvic limb lameness 2.5-week duration. Orthopaedic examination revealed an abnormal gait with impaired ability to support weight on the limb. There marked atrophy quadriceps muscles. Neurological absent patellar reflex and decreased sensation in cutaneous zone saphenous ner...

Background Morphea is a subtype of limited scleroderma characterized by atrophic changes. There are multiple treatment modalities for morphea, but all have success to restore atrophy. Objectives To evaluate the efficacy and safety paltelet rich plasma (PRP) skin changes in morphea such as (skin atrophy, dyspigmentation adnexal destruction) ultrasound Localized Scleroderma Cutaneous Assessment T...

cognitive impairment may be a common even at the onset of multiple sclerosis (ms). in this case-control study, we tried to find out the probable relationship between homocysteine levels and cerebral atrophy or cognitive impairment in patients with multiple sclerosis. one hundred fifty six patients who had ms according to mcdonald diagnostic criteria were included in this study. patients’ age, g...

abstract objective autosomal recessive spinal muscular atrophy (sma) is, after cystic fibrosis, the second most common fatal monogenic disorder and the second most common hereditary neuromuscular disease after duchenne dystrophy. the disease is characterized by degeneration of anterior horn cells leading to progressive paralysis with muscular atrophy. depending on the clinical type (werdnig- ho...