The effects of hydroalcoholic extract (HE) of Curculigo orchioides Gaertn. rhizome (Hypoxidaceae) and its alkaloidal and non-alkaloidal fractions (AF) and (NAF) were evaluated in carrageenan-induced paw edema experimental models of inflammation. The oral administration of HE, their AF and NAF fractions were used at doses of 100, 300 and 500 mg/kg. The effect produced by the HE, A...

BACKGROUND Osteoporosis is a complex bone disorder with a genetic predisposition, and is a cause of health problems worldwide. In China, Curculigo orchioides (CO) has been widely used as a herbal medicine in the prevention and treatment of osteoporosis. However, research on the mechanism of action of CO is still lacking. The aim of this study was to identify the absorbable components, potential...

BACKGROUND Curculigoside (CCG), one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn., is reported to prevent bone loss in ovariectomized rats. However, the underlying molecular mechanisms are largely unknown. Therefore, we investigated the effects of CCG on proliferation and differentiation of calvarial osteoblasts and discussed the related mech...

Diabetes mellitus is an incapacitating and often serious disease with increasing prevalence in rural populations throughout the world. In the current study, the putative antihyperglycemic and antihypolipidemic effects of C. orchioides were evaluated in comparison with those of glyclazide, a standard drug for therapy of diabetes mellitus. Diabetes was induced experimentally in 12-hr fasted rats ...

Bài báo mô tả phân tích định tính, lượng, đánh giá hoạt tính kháng khuẩn, chống oxy hóa của dịch chiết từ SC bằng phương pháp sắc ký lỏng cao áp (HPLC), Bertrand, Levanthal, Dược điển Việt Nam IV, Hoạt vi sinh vật kiểm được Nồng độ Chất ức chế Tối thiểu (MIC), oxi DPPH. Kết quả cho thấy: Sâm cau có chứa một số lớp chất học như là: saponin, phytosterol, flanonoid, đường khử tự do, béo, alkaloid,...

A procedure was developed for in vitro propagation of Curculigo latifolia through shoot tip culture. Direct regeneration and indirect scalp induction of Curculigo latifolia were obtained from shoot tip grown on MS medium supplemented with different concentrations and combinations of thidiazuron and indole-3-butyric acid. Maximum response for direct regeneration in terms of percentage of explant...

A new chlorine-containing glucosyl-fused compound, crassifoside H (1), was isolated from the EtOH extract of the rhizomes of Curculigo glabrescens. The structure was established on the basis of MS, IR, 1D and 2D NMR experiments. In addition, seven known compounds (2 – 8) were isolated and identified by spectroscopic analysis and comparison of their spectral data with those reported previously. ...