Cryptorchidism is one of the most common genital defects in dogs. This study investigated the effects of abdominal cryptorchidism on morphology, cell proliferation, and Sertoli cell condition in a dog with spontaneous unilateral cryptorchidism. Elective orchidectomy was performed on the abdominal right testis and the scrotal left testis. Significant reductions in numbers of spermatogonia, sperm...

The antioxidant effects of vitamins C and E on cryptorchidism-induced oxidative stress were investigated in male Sprague-Dawley rats. Forty rats (200-250 g) were randomly divided in a blinded fashion into five groups (n = 8). Group 1 was sham operated and treated with vehicle (corn-oil, 10 mL/kg). Groups 2, 3, 4, and 5 were rendered unilaterally cryptorchid and treated with vehicle (10 mL/kg), ...

background: the present study was designed to evaluate the survival and proliferation of spermatogonial stem cells from cryptorchid mouse testis in co-culture system over a 3 weeks period. materials and methods: sertoli and spermatogonial cells were isolated from bilateral cryptorchid mouse model testes. isolated spermatogonial cells were co-cultured with sertoli cells in minimal essential medi...

The biological term ridgeling is of uncertain derivation.' The word has been applied to various domestic animals; most commonly it refers to a male which has been "half castrated," i.e., has had only one testis removed, the other gonad being cryptorchid and relatively inaccessible to the operator. For reasons to be explained, such animals are useless and are often unmanageable and vicious. Norm...

Cryptorchidism, the failure of one or both testes to descend into the scrotum prenatally, occurs in 2.4%-5% of newborns. Many of these testes will descend spontaneously shortly after birth, but ~23% will remain undescended unless surgery is performed. Bilaterally cryptorchid men have a six times greater risk of being infertile when compared with unilaterally cryptorchid men and the general male...

Torsion of an undescended testis is uncommon. Torsion of a cryptorchid testicle presents a nonspecific symptomatology. Clinical suspicion indicates emergent surgical exploration, irrespective of Doppler ultrasound with its inherent false negative results. Management of the contralateral testis is controversial. We emphasize the need of a complete physical examination of the child who goes to th...

Lysosome-rich particles prepared from adult rat testes but not from liver released large amounts of various lysosomal enzymes into the supernatant medium when they were incubated at 37” at physiological PH. Evidence was presented that the thermally sensitive lysosomes were present in advanced germinal cells but not in spermatogonia. Lysosomal rich particles isolated from regressed testes, obtai...

Rats were surgically made bilaterally cryptorchid and after 4-8 days the testes were returned to the scrotum. After 70 days fertility was tested by pairing with females. Fertility was restored in 5/6 rats with testes cryptorchid for 4 or 5 days, but only 2/9 were fertile when the duration of cryptorchidism was 6-8 days. The sterility was due to irreversible degeneration of the spermatogonial st...

Objectives: To evaluate the results obtained with the technique of distal spermatic vessel ligation in children with upper or intra-abdominal undescended testis. Methods: Analysis of cryptorchid patients treated with Koff-Sethi technique for orquiopexy. Patient series: 15 children with unior bilateral cryptorchidism. Postoperative gonad viability was evaluated on the basis of clinical data, phy...