PAMELA (Particle Accelerator for MEdicaL Applications) is a design study of a novel accelerator for cancer therapy using protons and carbon ions. The accelerator utilizes the nonscaling Fixed Field Alternating Gradient (FFAG) principle and features superconducting combined-function magnets with dipole, quadrupole, sextupole and octupole field components for steering the ion beam. The proton rin...

Green fluorescent protein (GFP) and its variants, such as enhanced GFP (EGFP), have been introduced into mammalian cells by transgenes, e.g., to distinguish donor from host cells after transplantation. Free GFP is extremely soluble and leaks out from liquid-covered cryostat sections so that fixation of whole organs before sectioning has been mandatory. This precludes the analysis of serial sect...

' Martuza RL, Miller DC, MacLoughlin DT. Estrogen and progestin binding by cytosolic and nuclear fractions of human meningiomas. J Neurosurg 1985;62:750-6. 2Van Netten JP, Algard FT, Coy P, et al. Estrogen receptor assay on breast cancer microsamples. Implications of percent carcinoma estimation. Cancer 1982;49:2383-8. 3Ironside JW, Battersby RDE, Dangerfield VJM, Parsons MA, Timperley WR, Unde...

The liquid Argon TPC (LArTPC) technology is used in DUNE, the Deep Underground Neutrino Experiment, to achieve its goals as leading-edge international experiment for neutrino science and proton decay studies. first 10 k-ton DUNE far detector module will employ wired-based anode planes with cold readout electronics (CE) installed inside cryostat. CE developed cryogenic temperatures (77-89K) oper...