A randomized crossover trial of a new form of pediatric rehabilitation was conducted with 18 children with hemiparesis. Half were randomly assigned to receive pediatric constraint-induced therapy involving constraint of the functional upper extremity and intensive therapy with the hemiparetic upper extremity. Controls received conventional physical and occupational therapy and then were crossed...

In crossover trials, patients receive two or more treatments in a random order in different periods. The sample size determination is often an important step in planning a crossover study. This paper concerns sample size calculations in 2x2 crossover trials, with random patient effects and no interaction between the treatment and the patient under two scenarios, namely the exact and the large s...

purpose : to determine the distribution of iris colors in the population of tehran and to assess possible associations between iris color and ocular disorder methods : through a stratified random cluster sampling approach, 160 clusters were selected in different municipality districts of tehran, and the approached households were invited to a clinic. after the initial interview, all participant...

OBJECTIVES To determine patient preferences and cost differences between home-based and hospital-based chemotherapy. DESIGN Randomised crossover trial. SETTING A tertiary cancer hospital in Melbourne, Victoria. PARTICIPANTS 20 patients who required chemotherapy suitable for administration at home. INTERVENTIONS Patients were assigned at random to receive their first chemotherapy treatme...

BACKGROUND Translating a question into a query using patient characteristics, type of intervention, control, and outcome (PICO) should help answer therapeutic questions in PubMed searches. The authors performed a randomized crossover trial to determine whether the PICO format was useful for quick searches of PubMed. METHODS Twenty-two residents and specialists working at the Radboud Universit...

BACKGROUND The cluster randomised crossover (CRXO) design is gaining popularity in trial settings where individual randomisation or parallel group cluster randomisation is not feasible or practical. Our aim is to stimulate discussion on the content of a reporting guideline for CRXO trials and to assess the reporting quality of published CRXO trials. METHODS We undertook a systematic review of...

more than eighty percent of patients with coronary heart diseases (chd) have conventional risk factors. prevalence of well known risk factors seems to show a different pattern in younger patients and individual above 55 years. to evaluate the pattern of conventional chd risk factors in healthy individuals in two different age groups. a large scale population based survey of 31999 individuals fr...

background& aims: the mortality rate for breast cancer is directly related to the stage of disease at diagnosis. the present study aimed to determine the influencing factors on knowledge, attitudes, and practices of women regarding breast cancer and its screening methods.material & methods: in a cross- sectional study, evaluated 383 women referring health centers of ilam. sampling was d...