introduction: heart failure is a major hazard for public health. despite recent advance in medical therapy, there is not enough information on the outcome of off-pump coronary artery bypass (opcab) and medical therapy on the patients with severe ventricular dysfunction and triple-vessel (cad). this study aimed to compare treatment outcomes and mortality rate in patients undergoing off-pump coro...

  Introduction: Aortic valve sclerosisis considered as a manifestation of coronary atherosclerosis. Recent studies demonstrated an association between aortic valve sclerosis and obstructive coronary artery disease. The purpose of this study was to evaluatethe correlation betweenaortic valve sclerosis andobstructive coronary artery disease and the extent of coronary artery disease in patients ho...

purpose: due to unhealthy lifestyles, there has been an increase in the prevalence of coronary artery disease (cad) and a reduction in its age of onset. given the high cost of diagnosis and treatment of cad, there is an urgent need to teach people strategies helpful in changing their lifestyles as this can help reduce the risk factors of the disease. therefore, the goal of the present study was...

background: coronary artery disease (cad) is the major cause of mortality and morbidity worldwide. the aim of this study was to explore the effect of resveratrol (res) on canonical β-catenin/wnt and forkhead box o (foxo) pathways in cad patients.method: we performed this study on 10 metabolic syndrome patients with three-vessel cad and 10 sex-aged matched healthy subjects. the effects of res on...

the cd30 antigen seems to play a costimulatory role in maintaining the physiological balance between t-helper (th)1/th2 immune responses. in this study, plasma and in vitro soluble cd30 (scd30) secretion was investigated in patients with coronary artery disease (cad) as a plausible marker of dysregulated immune response. twenty one patients with angiographically confirmed cad and 31 healthy con...

introduction : significant left main coronary artery stenosis jeopardizes the entire myocardium of the left ventricle and has the worst prognosis of any form of coronary artery disease. coronary-artery bypass grafting (cabg) has been considered as the standard therapeutic approach for such patients. there are limited data on the safety and effectiveness of percutaneous coronary intervention (pc...

introduction: this study aimed to evaluate the effects of four-time inflation of the stent balloon at nominal pressure on optimal stent expansion in resistant lesions. materials and methods: this interventional study was conducted on 39 patients with coronary artery lesions, in whom zotarolimus-eluting stents (n=20), paclitaxel-eluting stents (n=11) and other stents (n=8) were deployed four tim...

background: coronary artery disease is recognized as one of the three major causes of mortality around the world. the role of inflammation in producing coronary artery disease has been established in previous studies. since periodontitis, which is highly prevalent, is considered as a cause of inflammation, its influence on producing coronary artery disease was investigated in the present study ...

this study was performed to assess the clopidogrel activity in inhibition of platelet aggregation in suspected angina patients on a daily dosag of 75 mg of clopidogrel for at least 7 days. this clinical trial was conducted in the outpatients department of cardiology, post graduate medical institute, lady reading hospital, peshawar from 15th october 2007 to 20th december 2007. we included 105 su...