Plasma creatine phosphokinase (GPK) was estimated from unmedicated schizophrenics to evaluate its significance in the diagnosis. The mean value of CPK in schizophrenics is 78.41±5.78 IU/L (n=49) as against control value of 27.45±2.27 IU/L (n = 36). The statistical analysis showed significance (p<0.05). The study finds its importance in view of the earlier reports suggesting the diagnostic value...

Hawk, P. B., Oser, B. L. & Summerson, W. H. (1947). Practical Phy8iotogical Chemi8try. London: Churchill. Heilbrunn, L. V. (1947). An Outline of General Phy8iology. Philadelphia: Saunders. Hoagland, H. & Stone, D. (1948). Amer. J. Phy8iol. 152, 423. Klein, J. R. & Olsen, N. S. (1947). J. biol. Chem. 167, 747. Krebs, H. A. (1950). Biochim. biophy8. Acta, Am8t., 4, 249. Krebs, H. A. & Eggleston, ...

The specificity of serum CPK-MB for acute myocardial infarction was examined by retrospective analysis of 401 consecutive patients admitted to a Coronary Care Unit over a three and one-half year period with suspected infarction in whom the isoenzyme was subsequently detected. Four patients (1% ) who died during the hospital admission had no autopsy evidence of acute myocardial infarction. All f...

The present study has investigated the effectiveness of staged-preconditioning, in both remote and target organs. After IP the myocardial release of the biochemical markers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB), cardiac troponin T (cTnT) and lactate dehydrogenase (LDH) were evaluated in patients who underwent CABG, with and without staged-preconditioning. Sixt...

Human whole mouth saliva (WMS) is secreted by salivary glands, namely parotid, submandibular/sublingual and other minor glands of the oral cavity. It is secreted in a systematic way, and contain informative proteins and peptides for the early detection of contagious diseases and organ-related diseases. The role of WMS as a liquid biopsy for the detection of cardiovascular diseases (CVD) through...

Myocardial infarction is a previously unreported complication of treatment with racemic epinephrine that is used commonly in the emergency department for severe respiratory distress in bronchiolitis or croup syndrome. We describe a pediatric patient who presented with the croup syndrome and severe respiratory distress that required multiple doses of nebulized racemic epinephrine in the emergenc...

Serum CPK-MB iosenzyme activity was measured serially after mercury embolization of the left circumflex coronary artery in five baboons and after clinical acute myocardial infarction (AMI) in 20 patients. The calculated amount of enzyme released into the baboons' circulation (CPK-MBR) correlated well (r = 0.991) with the amount of MB isoenzyme depleted from the myocardium (CPK-MBD) when a previ...