We have studied the electrophoretic characteristics of a creatine kinase (CK, EC 2.7.3.2) isoenzyme, macro creatine kinase type 2 (MCK-2), in the serum of 42 patients with carcinoma of the colon. The patients could be divided into three subgroups by the intensity of the MCK-2 band (nine high, nine medium, and 24 low intensity), but we detected no correlation between the isoenzyme activity and t...

Electrophoretograms of atypical creatine kinase (EC 2.7.3.2, CK) isoenzymes may be difficult to interpret. In addition, their presence may cause discrepancies between results by immunological determinations for mass or activity and those by electrophoresis. Here we outline procedures to use in characterizing apparently atypical CK isoenzymes observed after electrophoresis, as illustrated by a C...

conclusions in patients without clear signs of myocardial infarction, even mild co poisoning was associated with quantifiable circulating levels of hs-ctnt when tnt was measured using a highly sensitive assay in the current study patients. plasma levels of the hs-tnt and ck-mb assays were not correlated with the cohb levels in the current study patients. results the mean age of the patients was...

objective(s):paclitaxel is a potent chemotherapy agent with severe side effects, including allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which may limit its use and lower its efficiency. the cardioprotective effect of royal jelly was investigated on paclitaxel-induced damages. materials and methods:adult male wistar rats were divided into control and te...

the aim of this study was to determine the effect of rest intervals between two resistance exercise protocols (with similar volume and intensity) on plasma antioxidant capacity (tac) and creatine kinase (ck). for this purpose, 20 untrained subjects voluntarily participated in the research and randomly assigned to one of the two resistance exercise groups with 2-minute rest interval and 4-minute...

this study intended to compare the effect of consuming creatine and mixed creatine-carbohydrate supplementations on the anaerobic power and cellular damage indices (ck, ldh) in males aged between 15 and 18 in the city of kouhrang. for this purpose, 36 subjects (mean age 16.42±0.90 yrs, weight 54.85±9.96 kg, and height 167.75±8.28 cm) were selected by available method. first, blood samples were ...

The response of total creatine kinase (CK) and the creatine kinase isoenzyme (CK MB) was studied in 22 male post-infarction patients (three to six months after myocardial infarction) after a functional graded exercise test, before entering a rehabilitation programme. Eleven subjects (group A) completed the test without developing significant electrocardiographic abnormalities. Eleven subjects (...

Alterations of serum creatine kinase isoenzymes were observed in five cases of prostatic carcinoma. Creatine kinase isoenzyme BB was found in the serum of two of three cases with metastases. Its presence in serum does not seem to be related to acid phosphatase activity but seems associated with extension of the tumor to other tissues. Preliminary studies on effusions from patients with malignan...

We describe a procedure for purification of creatine kinase (EC 2.7.3.2) MB isoenzyme (CK-MB) from human cardiac muscle by preparative electrophoresis on polyacrylamide gel. From a 50-g portion of human myocardium we isolated 21 mg of CK-MB, which had a specific creatine kinase activity of 405 kU/g. The CK-MB exhibited an enzyme band on polyacrylamide gel electrophoresis (PAGE) with staining fo...