نتایج جستجو برای: cranial irradiation

تعداد نتایج: 89228  

Journal: :Pediatric Neurology Briefs 1991

2011
Alireza Shirazi Gholam Hasan haddadi Fahimeh Asadi-Amoli Saeideh Sakhaee Mahmoud Ghazi-Khansari Abolghasem Avand

OBJECTIVE Ocular morbidity is widely observed when radiotherapy includes the orbit. Oxidative stress generated by irradiation is responsible for this complication. In different studies, it has been shown that melatonin has antioxidative properties and a radioprotective role. The aim of this study was to evaluate the antioxidant role of melatonin against radiation-induced oxidative injury in rat...

A. Ahlatci, A. Demirci, A. Dirier, Abdurahman Kuzhan, E. Demir, E. Saricicek, H.E. Alkis, K. Cinar, M. Tarakcioglu, T. Demir,

Background: Our purpose was to investigate propolis and its component caffeic acid phenethyl ester (CAPE) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation (IR). Materials and Methods: Fifty-four male albino Sprague-Dawley rats, divided into six groups, were designed as normal control group, cranial irradiation of 5 Gray alone, irradiation plus CAPE, irradi...

Journal: :Japanese journal of clinical oncology 2014
Lei Fu Fang Liu Hui Fu Liqing Liu Shuanghu Yuan Yongsheng Gao Zheng Fu Jinming Yu

OBJECTIVE We investigated the correlation between circulating tumor cells and the incidence of brain metastases as a first site of recurrence among patients with small-cell lung cancer after systemic chemoradiotherapy and prophylactic cranial irradiation. In addition, we assessed the contribution of circulating tumor cells for planning the appropriate total dose of prophylactic cranial irradiat...

2008
Susanna Rosi Marta Andres-Mach Kelly M. Fishman William Levy Ryan A. Ferguson John R. Fike

Therapeutic irradiation of the brain is commonly used to treat brain tumors but can induce cognitive impairments that can severely affect quality of life. The underlying mechanisms responsible for radiation-induced cognitive deficits are unknown but likely involve alterations in neuronal activity. To gain some mechanistic insight into how irradiation may affect hippocampal neurons known to be a...

Journal: :International journal of radiation oncology, biology, physics 2007
Pètra M Braam Cornelis P J Raaijmakers Chris H J Terhaard

PURPOSE To analyze the cranial distribution of level II lymph nodes in patients with laryngeal cancer to optimize the elective radiation nodal target volume delineation. METHODS AND MATERIALS The most cranially located metastatic lymph node was delineated in 67 diagnostic CT data sets. The minimum distance from the base of the skull (BOS) to the lymph node was determined. RESULTS A total of...

Journal: :Hormone research in paediatrics 2011
Shlomit Shalitin Moran Gal Yacob Goshen Ian Cohen Isaac Yaniv Moshe Phillip

AIM To evaluate the rates of endocrine abnormalities in survivors of childhood brain tumors and identify risk factors. METHODS The medical charts of patients were reviewed for background, disease-related and treatment-related data. Endocrine dysfunction was determined by clinical and laboratory evaluation. RESULTS The study group included 114 patients with a mean age of 15.57 ± 5.93 years. ...

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