OBJECTIVE To determine whether there is a benefit in clinical outcomes with the use of topical corticosteroids as adjunctive therapy in the treatment of bacterial corneal ulcers. METHODS Randomized, placebo-controlled, double-masked, multicenter clinical trial comparing prednisolone sodium phosphate, 1.0%, to placebo as adjunctive therapy for the treatment of bacterial corneal ulcers. Eligibl...

BACKGROUND Tourette syndrome is a neurologic disorder that is characterized by repetitive muscle contractions that produce stereotyped movements or sounds. Approximately 50% of individuals with TS also exhibit obsessive-compulsive behaviors including eye rubbing. We report a case of bilateral self-induced keratoconus in a patient with TS, associated with compulsive eye rubbing. CASE PRESENTAT...

Laser Refractive Cataract Surgery With a Femtosecond Laser After Penetrating Keratoplasty: Case Report Cataract surgery after corneal transplant must minimize endothelial cell damage because postoperative transplant cell counts are lower than those of normal corneas. As the femtosecond laser was successfully introduced in cataract surgery,1,2 we applied this technology in an eye that had a prev...

PURPOSE To look at the correlation between many factors (time of hospitalization, floppy eyelid syndrome, trichiasis, open lacrimal puncta, symblepharon, and aqueous tear deficiency) and corneal complications in Stevens-Johnson syndrome (SJS). DESIGN Observational cases series. PATIENTS Clinical data were retrospectively reviewed from 38 patients (32.7+/-20.1 years old) with SJS (n = 11) an...

purpose: to investigate indications and methods of surgery in corneal transplantation in labbafinejad medical center from 2007 to 2009. methods: records of 1083 patients who had undergone corneal transplantation from 2007 to 2009 were reviewed. age, sex and indication and type of surgery were evaluated. results: patients included 709 (65.5%) male and 374 (34.5%) female subjects with mean age of...

Bacterial keratitis is a serious ocular infectious disease that can threaten vision. The disease generally progresses rapidly and can lead to corneal scar, stromal abscess formation, perforation, and dissemination to adjacent tissues if not treated properly. Recent studies showed that corneal collagen crosslinking (CCC) using ultraviolet-A/riboflavin is effective in the treatment of bacterial k...

Connective Tissue Growth Factor (CTGF) and Transforming growth factor-β1 (TGF-β1) are key growth factors in regulating corneal scarring. Although CTGF was induced by TGF-β1 and mediated many of fibroproliferative effects of TGF-β1, the signaling pathway for CTGF production in corneal scarring remains to be clarified. In the present study, we firstly investigated the effects of c-Jun N-terminal ...

The purpose of this report is to provide a comprehensive account an exceptional case involving the presentation congenital rubella syndrome (CRS) in newborn. Furthermore, it aims document successful regression CRS through medical treatment alone. We present five-day-old infant who was referred our facility as case. patient presented with bilateral white corneal opacity, which observed shortly a...

The existing acute shortage of good quality donor corneas in a developing country like India, prompted us to attempt customised component corneal transplantation. Using this surgical strategy, one corneoscleral button was used for three recipients. Anterior and posterior lamellar discs were used for anterior lamellar keratoplasty and Descemet's stripping endothelial keratoplasty in patients wit...

Rejection of corneal grafts was produced in rabbits after skin from the corneal donor was grafted subcutaneously. Clinical observations showed that the graft sickness started at the periphery of the graft after blood vessels from the host cornea reached the scar. Histologic studies demonstrated that the scar tissue was first invaded by vessels and infiltrated by lymphocytes, monocytes, and plas...