A 3-year-old boy presented with acute corneal hydrops on the left eye and spontaneous corneal rupture on the right eye. A diagnosis of brittle cornea syndrome was confirmed by molecular analysis. A novel mutation, the homozygous variant c.17T>G, p.V6G, was found in the gene for PR-domain-containing protein 5 (PRDM5) in exon 1. Brittle cornea syndrome is a rare connective tissue disease with typ...

purpose: to compare visual and refractive outcomes as well as graft survival after penetrating keratoplasty (pk) in keratoconic patients with or without acute hydrops. methods: in this comparative interventional case series, 14 eyes of 14 keratoconic patients with acute hydrops (group 1) and 37 eyes of 37 keratoconic patients with no history of acute hydrops (group 2) underwent pk. visual acuit...

Purpose. To demonstrate keratoconus-like hydrops after laser in situ keratomileusis (LASIK) by optical coherence tomography (OCT). Patient and Methods. A 21-year-old man received uneventful bilateral LASIK. On slit lamp examination or corneal topography there were no signs of fruste keratoconus. The preoperative corneal thickness was 587-mum OD and the calculated ablation for two treatments was...

AIM To improve the deep lamellar keratoplasty technique. METHOD For the easy and reliable perfomance of deep lamellar keratoplasty (DLKP), detachment of Descemet's membrane through the corneal limber flap was improved. To expose Descemet's membrane, the parenchyma was detached by hydrodelamination through a sclerocorneal flap made in the corneal limbs. The parenchyma was removed after the pse...