Various clinical disorders and injuries, such as chemical, thermal, or mechanical injuries, may lead to corneal loss that results in blindness. PURPOSE: The aims of this study were to differentiate human buccal mucosa (BMuc) into corneal epithelial-like cells, to fabricate engineered corneal tissue using buccal mucosal epithelial cells, and to reconstruct a damaged corneal epithelium in a nude ...

The effects of sclerocorneal limbal stem cell autograft transplantation in dogs with corneal wounds were studied. Eighteen dogs were divided in two groups (GI and GII). The animals of GI (n=12) underwent limbal transplantation 30 days after the destruction of limbal stem cells. The dogs of GII (n=6) only underwent destruction of stem cells (control group). Light microscopy examination of the ri...

PURPOSE To report the clinical outcomes of deep anterior lamellar keratoplasty (DALK) when sterile gamma-irradiated acellular corneal tissues (VisionGraft) are used in combination with amniotic membrane transplantation (AMT) for intractable ocular surface diseases. METHODS The medical records of fifteen patients who had DALK with AMT were retrospectively reviewed. Indications for surgery incl...

BACKGROUND To investigate the outcome and prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty (PKP) treated with topical and systemic steroids. METHODS Fifty-eight eyes in 58 patients with severe corneal graft rejection following PKP were treated with topical and systemic steroids. Factors affecting the reversibility and mainte...

purpose: to report the outcomes of goniotomy in young children with primary congenital glaucoma. methods: this retrospective study included 26 eyes of 19 patients with primary congenital glaucoma who underwent goniotomy as the initial procedure. all patients were aged less than 3 years and had no history of previous ocular surgery. the main outcome measures were intraocular pressure (iop), cup/...

BACKGROUND The purpose of this study is to report the safety and efficacy of a new application of collagen cross-linking using a novel device to achieve predictable refractive myopic changes in virgin corneas. METHODS Four cases were treated with a novel device employing very high-fluence collagen cross-linking applied in a myopic pattern. Prior to treatment, riboflavin solution was applied t...

Contact lens type amniotic membrane (CLAM) is a promising new approach to using in ophthalmology. It can be used treat range of ocular surface disorders, including dry eye disease, corneal ulcers, and chemical burns. CLAM help reduce inflammation, promote epithelialization wound healing, improve clarity vision. Its ease handling application, combined with its potential therapeutic benefits, mak...

BACKGROUND To protect from erosion of the tube in glaucoma drainage device (GDD), the tube is covered by a biologic tissue which is roofed by the conjunctiva. Sclera, pericardium, dura mater and cornea are available as a patch graft. Drawbacks of some of these materials may include high cost and poor appearance. The purpose of this study is to report the long-term outcomes of partial thickness ...

purpose: to report the outcomes of manual lamellar keratoplasty (lkp) in patients with delayed-onset mustard gas keratitis (mgk) and compare visual outcomes between subgroups with simultaneous or sequential klal and lkp. methods: in this retrospective, interventional study, 52 eyes of 37 male survivors of chemical warfare with mgk who underwent lkp were included. the results were evaluated with...