Effects of iron and copper impurities on the amount of precipitated oxygen and the oxide precipitate and stacking fault densities in Czochralski-grown silicon have been studied under varying thermal anneals. Silicon wafers were intentionally contaminated with iron or copper and subsequently subjected to different two-step heat treatments to induce oxygen precipitation. The iron contamination le...

The blood serum copper level and the phonation start were investigated in sixteen male subjects with developmental stuttering (mean age = 25.8 years). A statistically significant decrease in blood serum copper level was revealed in the stutterers under study. The differences between their mode and mean values and that of the control group were 4.6 mumol/l and 3.1 mumol/l, respectively. The nega...

In order to measure serum copper concentration, 163 adult males working at different units of copper plant from a total population of 671, were selected by simple random sampling. Eighty three subjects working at melting foundry, 49 in extrugen- rolling and 31 at administrative service untils. Eighty four adult male natives of Kerman and it's suburbs were randomly choosen as control group, seru...

The trace element copper serves as cofactor for many enzymes but is toxic at elevated concentrations. In bacteria, the intracellular copper level is maintained by copper efflux systems including the Cue system controlled by the transcription factor CueR. CueR, a member of the MerR family, forms homodimers, and binds monovalent copper ions with high affinity. It activates transcription of the co...

serum level of zinc, copper, β-carotene, vitamin a, and concentrations of zn and cu in hoof of 97multiparous holstein dairy cows with different locomotion scores (lss) were evaluated. simultaneously, znand cu concentrations of close up, fresh and high yielding cattle rations were 77, 94, 75 and 31, 28, 22 ppm, respectively. based on lss, despite normal serum copper levels in all three groups, w...

wilson's disease is a rare but treatable condition with variable clinical presentations. its diagnosis depends on a combination of clinical and laboratory findings. we evaluated the clinical and laboratory findings in children with wilson's disease (wd). twenty -seven children (4-14 years, 59.2 % male, 40.7% female) with confirmed wd were evaluated between 1994 and 2003 at imam khomei...

Two cooperative experiments were conducted by the North Central Regional Committee on Swine Nutrition. Ten stations participated and utilized 125 pens (802 pigs) in experiment l to evaluate the effect of high dietary copper levels and vitamin E on performance, hemoglobin level and liver copper stores of pigs. In experiment 2, 142 pens (934 pigs) were used to evaluate the effect of different lev...

BACKGROUND Copper and zinc are the elements with numerous physiological activities. Copper (Cu) has an important role in angiogenesis and acts by increasing Vascular Endothelial Growth Factor (VEGF). Serum levels of copper will be increased in cancer incidence, progression and recurrence. The aim of this study was to measure blood levels of copper, zinc, and the ratio of Cu /Zn, as well as VEGF...

The basic amino acid histidine inhibited yeast cell growth more severely than lysine and arginine. Overexpression of CTR1, which encodes a high-affinity copper transporter on the plasma membrane, or addition of copper to the medium alleviated this cytotoxicity. However, the intracellular level of copper ions was not decreased in the presence of excess histidine. These results indicate that hist...

Wilson's disease (hepato-lenticular degeneration) is now known to be associated with an inborn error of metabolism. The following biochemical abnormalities have been repeatedly confirmed in patients suffering from the disease (Scheinberg, 1956; Bickel, Neale, and Hall, 1957): Increased content of copper in the liver, brain, and other tissues, increased urinary excretion of copper, a decreased l...