Background: A novel drug delivery system using poly (ε-caprolactone) - poly (ethylene glycol) -poly (ε-caprolactone) (PCL-PEG-PCL) was established in this study. Methods: Ceftriaxone (CTX) was encapsulated within PCL-PEG-PCL nanoparticles by a double emulsion technique (w/o/w), leading to creation of ceftriaxone-loaded PCL-PEG-PCL (CTX/PCL-PEG-PCL) polymersomes. The resulting polymersomes...

Neat and hybrid polyamide 12 (PA12) based powders are important raw materials for additive manufacturing. This study describes a facile method the synthesis of pure, copolymeric microparticulate on one-pot activated anionic ring-opening polymerization (AAROP) laurolactam in solution. The results reveal possibility to obtain good yields, reaction times 2 h temperatures up 110°C neat PA12 micropa...

Complex coacervate microdroplets are finding increased utility in synthetic cell applications due to their cytomimetic properties. However, their intrinsic membrane-free nature results in instability that limits their application in protocell research. Herein, we present the development of a new protocell model through the spontaneous interfacial self-assembly of copolymer molecules on biopolym...