BACKGROUND Most corneal damage induced by contact lenses is due to interference with corneal oxygenation. OBJECTIVE To investigate the effect on the rabbit cornea of a rigid gas-permeable contact lens with a newly designed periphery. METHOD We fitted New Zealand white rabbits (n = 12) with RGP contact lenses that were identical in all respects except for the design of the periphery. In each...

BACKGROUND Visual outcome following repair of post-traumatic corneal perforation may not be optimal due to presence of irregular keratometric astigmatism. We performed a study to evaluate and compare rigid gas permeable contact lens and spectacles in visual rehabilitation following perforating corneal injuries. METHOD Eyes that had undergone repair for corneal perforating injuries with or wit...

This paper describes a simple method for fabricating a variable-focus lens by using PDMS (polydimethylsiloxane) and filling with liquid for the variable-focus lens. The lens diameter of 2-mm was designed in this experiment and expected to reach the focal length in the range of 3 ~ 12 mm. The theoretical value between the liquid volume and the lens contact angle at different focal lengths were s...

This paper describes a simple method for fabricating a variable-focus lens by using PDMS (polydimethylsiloxane) and filling with liquid for the variable-focus lens. The lens diameter of 2-mm was designed in this experiment and expected to reach the focal length in the range of 3 ~ 12 mm. The theoretical value between the liquid volume and the lens contact angle at different focal lengths were s...

We studied the topographical, macrostructural, and fluorescein staining characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of hydrophilic (soft) contact lenses. Fifty soft contact lens wearers with elevated conjunctival papillae greater than 0.3 mm in diameter were studied. Topographic characteristics recorded were distribution and number of papilla...

PURPOSE Many soft contact lens wearers have symptoms or signs that compromise successful lens wear. This study estimated the prevalence of problems in current wearers of soft contact lenses and tested the effect of refitting patients with senofilcon A silicone hydrogel lenses (ACUVUE Oasys). METHODS Prevalence was estimated from 1,092 current lens wearers for frequent or constant discomfort o...

PURPOSE The purpose of this work was to develop an enzymatic method of quantification of cholesterol and cholesterol esters derived from contact lenses, both in vitro and ex vivo. METHODS Lotrafilcon B (O2 Optix; CIBA Vision, Inc., Duluth, GA) and galyfilcon A (Acuvue Advance; Vistakon, Inc., Jacksonville, FL) silicone hydrogel contact lenses were independently incubated in cholesterol oleate...

BACKGROUND The contaminated contact lens provides Pseudomonas aeruginosa an ideal site for attachment and biofilm production. Continuous contact of the eye to the biofilm-infested lens can lead to serious ocular diseases, such as keratitis (corneal ulcers). The biofilms also prevent effective penetration of the antibiotics, which increase the chances of antibiotic resistance. METHODS For this...