AIM To determine prognostic factors for recurrence of disease and tumour related mortality in patients with conjunctival melanoma. METHODS A retrospective analysis of clinical and histopathological data of 69 patients with histologically verified conjunctival melanoma. RESULTS As univariate analysis showed, significant risk factors for the development of recurrence were: irregular pigmentat...

Melanoma of the conjunctiva is a rare tumor with incidence from 0,03 to 0,08 cases per 100000 white population. Metastatic malignant melanoma represents approximately 5% of all secondary malignant lung tumors. We report the unexpected discovery of a pulmonary and pleural metastasis from a conjunctival melanoma in a young subject.

BACKGROUND Conjunctival melanoma is a relatively rare ocular malignancy with substantial associated morbidity and mortality. METHODS More than 100 articles on conjunctival melanoma were reviewed, including most of the relevant recent publications cited in a current MEDLINE search. The author's experience with conjunctival melanomas is also incorporated in this review. RESULTS Recognition of...

BACKGROUND To report our experience with sentinel lymph node biopsy for staging patients with conjunctival melanoma. METHODS A prospective review of patients with conjunctival melanoma who underwent sentinel lymph node biopsy at St Bartholomew's Hospital from May 2008 to May 2012. The selection criterion for sentinel node biopsy depended on the tumour thickness (≥2 mm) and location of the con...

I t has been proposed that ocular surface melanomas should be treated by simple local excision and cryotherapy to the conjunctival borders. Based on what is known of the biology of both cutaneous and mucosal melanomas, however, we consider it unlikely that such a technique, without deep scleral clearance, will reliably eliminate ocular surface melanomas. Indeed, the documented behavior of melan...

Originally received: April 11, 2016. Final revision: April 27, 2016. Accepted: April 27, 2016. Available online: June 1, 2016. Manuscript no. 2016-739. 1 Singapore National Eye Centre, Singapore, Republic of Singapore. 2 Singapore Eye Research Institute, Singapore, Republic of Singapore. 3 Department of Ophthalmology and Visual Sciences, Duke-NUS Medical School, Singapore, Republic of Singapore...