Congenital rubella syndrome (CRS) can occur in children whose mothers contract the rubella virus, sometimes called German measles, during pregnancy [2]. Depending on the gestational period when the mother contracts rubella, an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. The most severe effects of the virus on fetal development occur when the ...

Congenital rubella syndrome (CRS) can occur in children whose mothers contract the rubella virus, sometimes called German measles, during pregnancy [2]. Depending on the gestational period when the mother contracts rubella, an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. The most severe effects of the virus on fetal development occur when the ...

Background and Aims: Vaccine is available, but fetal infection with rubella virus is still a main cause of congenital birth defects and mental retardation in many countries. Mass vaccination campaigns and Expanded Program of Immunization (EPI) have increased vaccine coverage in the world with a substantial impact on the reduction of rubella infections, such as Congenital Rubella Syndrome (CRS)....

Background and Aims: Rubella virus is a human pathogen that causes congenital rubella syndrome (CRS) when infection occurs during early pregnancy. Vaccination programs have been remarkably successful in controlling natural rubella infection and CRS. Moreover, ongoing surveillance for all cases of rubella and CRS is a vital component of a prevention program. Although the WHO recommends the use o...

OBJECTIVE To describe rubella outbreaks and control strategies in the Brazilian state of Rio Grande do Sul before rubella elimination. METHODS We analyzed rubella and congenital rubella syndrome surveillance data for the state of Rio Grande do Sul and calculated age- and gender-specific incidence of confirmed rubella cases in 2007. We obtained data on measles-rubella doses administered during...

Congenital rubella syndrome (CRS) can occur in children whose mothers contract the rubella virus, sometimes called German measles, during pregnancy [2]. Depending on the gestational period when the mother contracts rubella, an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. The most severe effects of the virus on fetal development occur when the ...

Congenital rubella syndrome (CRS) can occur in children whose mothers contract the rubella virus, sometimes called German measles, during pregnancy [2]. Depending on the gestational period when the mother contracts rubella, an infant born with CRS may be unaffected by the virus or it may have severe developmental defects. The most severe effects of the virus on fetal development occur when the ...

Abbreviations: MMR: Measles, Mumps and Rubella; WHO: World Health Organization; SSPE: Subacute Sclerosing Panencephalitis; PAHO: Pan American Health Organization; CRS: Congenital Rubella Syndrome; MR: Measles-Rubella; GSK: GlaxoSmithKline; EZ: Edmonston Zagreb; CEF: Chicken Embryo Fibroblast; IBD: Inflammatory Bowel Disease; CDC: Centers for Disease Control and Prevention; SSPE: Subacute Sclero...