BACKGROUND Quantitative PCR (qPCR) is a workhorse laboratory technique for measuring the concentration of a target DNA sequence with high accuracy over a wide dynamic range. The gold standard method for estimating DNA concentrations via qPCR is quantification cycle () standard curve quantification, which requires the time- and labor-intensive construction of a standard curve. In theory, the sha...

correct estimation of suspended sediment transported by a river is an important practice in water structure design, environmental problems and water quality issues. conventionally, sediment rating curve used for suspended sediment estimation in rivers. in this method discharge and sediment discharge or concentration related using regression relation that generally is exponential model. respect ...

ONE of the main problems in the use of continuously recorded dye dilution curves has been the calibration of the obtained curves. Methods involving measurements from the "tail" of the dilution curve are often inaccurate because in this portion of the curve the concentration of dye is low. Other methods of calibration involve determinations from a sample of blood withdrawn before or after the di...

resonance light scattering (rls) intensity of silver nanoparticles in the presence of sodium dodecylsulphate was quenched on addition of sulfasalzine. the quenching extent was shown to be proportional to the sulfasalazine concentration. effect of different parameters such as ph, volume and kind of buffer, silver nanoparticles concentration, sodium dodecylsulphate (sds) concentration, and waitin...

Submit Manuscript | http://medcraveonline.com Abbreviations: tmax: Time to Reach the Maximum Concentration; Cmax: Maximum Plasma Concentration; t1/2: Half-Life; AUC0-24: Area Under the Plasma Time Curve Up to Last Quantifiable Time; AUC0∞: Area Under the Plasma Time Curve Up to Time Infinity; kel: Elimination Rate Constant; NCDs: Non-Communicable Diseases; DGDA: Directorate General of Drug Admi...

The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both vancomycin efficacy and toxicity are likely to be related to the area under the plasma concentration-time curve (AUC). We assembled richly sampled vancomycin pharmacokinetic data from three studies comprising 47 adults with vari...