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Exogenous mechanical perturbations on living tissues are commonly used to investigate whether cell effectors can respond to mechanical cues. However, in most of these experiments, the applied mechanical stress and/or the biological response are described only qualitatively. We developed a quantitative pipeline based on microindentation and image analysis to investigate the impact of a controlle...

In addition to high pulmonary vascular resistance (PVR) and low pulmonary blood flow, the fetal pulmonary circulation is characterized by mechanisms that oppose vasodilation. Past work suggests that high myogenic tone contributes to high PVR and may contribute to autoregulation of blood flow in the fetal lung. Rho-kinase (ROCK) can mediate the myogenic response in the adult systemic circulation...

We studied the mouth opening response to appendicular compression in two groups of children. This study was performed with the intention of testing the semiologic role of the act of mouth opening following stimulation of various regions, based on the hand mouth reflex of Babkin. Group I was formed by 33 normal children who underwent monthly follow up assessments since birth; and group II consis...

In this paper Boolean filters and a variation of these, FIR-Boolean hybrid filters are proposed for realizing the prediction stages of a multiresolution lossless image compression structure. Optimal and adaptive Boolean filters are used for prediction in The proposed predictors performance is compared to the performance of other lossless multiresolution methods: the hierarchical interpolation s...

Efficient access to the inverted index data structure is a key aspect for a search engine to achieve fast response times to users’ queries. While the performance of an information retrieval (IR) system can be enhanced through the compression of its posting lists, there is little recent work in the literature that thoroughly compares and analyses the performance of modern integer compression sch...

Cardiac and skeletal muscle contraction lead to compression of intramuscular arterioles, which, in turn, leads to their vasodilation (a process that may enhance blood flow during muscle activity). Although endothelium-derived nitric oxide (NO) has been implicated in compression-induced vasodilation, the mechanism whereby arterial compression elicits NO production is unclear. We cannulated isola...

BACKGROUND The knee joint performs mechanical functions with various loading and unloading processes. Past studies have focused on the kinematics and elastic response of the joint with less understanding of the rate-dependent load response associated with viscoelastic and poromechanical behaviors. METHODS Forty-five fresh porcine knee joints were used in the present study to determine the loa...