• Objective: To assess process and outcome measures before and after a multifaceted intervention for patients hospitalized on the medical floor with community-acquired pneumonia (CAP). • Setting and participants: 1054 patients with CAP admitted to 12 acute care community hospitals from March 1998 to February 2000 (baseline, n = 517) and from October 2000 to March 2001 (postinter-

Background: Mycoplasma pneumoniae is one of the causes of upper and lower respiratory tract infections especially in children, and antibiotics affecting the cell wall do not affect this type of infection. This study aimed to evaluate the prevalence of Mycoplasma pneumoniae and macrolide resistance in children with community-acquired pneumonia in Kerman city. Methods: This cross-sectional study...

BACKGROUND AND OBJECTIVE To quantify the impact of different guideline implementation interventions to improve treatment of community-acquired pneumonia (CAP) in a hospital setting. METHODS Pubmed, the Cochrane Library, the Cochrane Effective Practice and Organization of Care specialized register, EMBASE and CINAHL. STUDY SELECTION Hospital-based trials studying the effect of guidelines on ...

Antibiotic guidelines for community-acquired pneumonia (CAP) often recommend broad-spectrum agents for severe pneumonia. While these may be entirely appropriate in terms of their spectrum of activity and efficacy, there is a risk that such recommendations could result in over-prescribing of broad-spectrum agents with consequent 'collateral damage', meaning superinfection by resistant pathogens,...

W here to treat a patient with community-acquired pneumonia (CAP) is probably the most important decision in the management of this condition. This is true in terms of patient outcomes and, definitely, in terms of costs. Therefore, all current European and American guidelines agree that the assessment of severity is the starting point in the management algorithm [1–5]. If the assessment is so c...

We conducted this study to compare clinical features, outcomes, and clinical implication of antimicrobial resistance in Klebsiella pneumoniae bacteremia acquired as community vs. nosocomial infection. A total of 377 patients with K. pneumoniae bacteremia (191 community-acquired and 186 nosocomial) were retrospectively analyzed. Neoplastic diseases (hematologic malignancy and solid tumor, 56%) w...

The pathogen has been found to cause a plethora of diseases such as blood stream infections, skin and soft tissue infections, pneumonia and hospital acquired postoperative wound infections [2]. Though the diseases are treatable by the usage of antibiotics, emergence of multi drug resistant strains have been reported worldwide, thereby complicating the treatment of infections caused by Staphyloc...

OBJECTIVE Gram negative bacilli are among the most important microbial agents involved in both hospital- and community-acquired infections. The quinolones are preferred antibacterial agents for the treatment of both community- and hospital-acquired urinary tract infections caused by gram negative bacilli because of their strong antibacterial effects, and because they can be administered both or...

Community-acquired methicillin resistant Staphylococcus aureus (MRSA) usually causes skin and soft tissue infections. However, community-acquired methicillin resistant S.aureus has been identified as a causative agent of many invasive infections like necrotizing fasciitis, pneumonia and bacteremia. Risk factors such as immunodeficiency and skin and soft tissue infections have been identified fo...

BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) isolates are increasingly frequent causes of skin and soft-tissue infections or invasive infections in many communities. METHODS Prospective surveillance for community-acquired S. aureus infections at Texas Children's Hospital was initiated on 1 August 2001. Infections meeting the definition of community-acquired were identified. D...