The biblical balm of Gilead (Commiphora gileadensis) was investigated in this study for anticancerous activity against tumor cell lines. The results obtained from ethanol-based extracts and from essential oils indicated that β-caryophyllene (trans-(1R,9S)-8-methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene) is a key component in essential oils extracted from the balm of Gilead. β-Caryophylle...

materials and methods thirty-two adult male wistar rats were randomly allocated to four groups: normal, diabetic, normal + extract of c. mukul and diabetic + extract of c. mukul groups with free access to regular rat diet. diabetes was induced in male rats by single interaperitoneal injection of 60 mg/kg stz. after the confirmation of diabetes, 300 mg/kg c. mukul extract was orally administered...

Oleo-gum resins such as frankincense and myrrh are some of the economically and culturally valuable products obtained from trees and shrubs of the genera Boswellia and Commiphora, respectively. They are important natural plant products used in several industries that include pharmacology, food, flavour, liqueur and beverage, cosmetics, perfumery and others. Moreover, frankincense and myrrh have...

Commiphora species are of high medicinal importance. They distributed in Saudi Arabia, mainly rocky habitats and regions under mountains, including the east Tihama, forming a distinct element flora. The present study focuses on botanical characterization five Commiphora, i.e., C. erythraea, gileadensis, kataf, myrrha, quadricincta. morphological characters for each were recorded comparatively, ...

The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroidism is although a little reversible yet it is normalized quickly after C. mukul treatment. These...

The title triterpene compound, C(23)H(32)O(4), isolated from Commiphora wightii features four trans-fused rings, among which the five-membered ring adopts an envelope conformation, the cyclo-hexene ring adopts a half-chair conformation and the two cyclo-hexane rings exist in chair conformations. The asymmetric unit contains two independent mol-ecules. Weak inter-molecular C-H⋯O hydrogen bonding...

The volatile components of the leaves of five Bursera species, B. copallifera, B. exselsa, B. mirandae, B. ruticola and B. fagaroides var. purpusii were determined by gas chromatography-mass spectrometry (GC-MS). Germacrene D was one of the predominant components (15.1-56.2%) of all of these species. Germacrene D has also been found in other Bursera species and some species of Commiphora, the s...

Phytochemical investigation of the whole plant of Commiphora mukul Engl. resulted in the isolation of two lignans, epiexcelsin (1) and 5′-demethoxyepiexcelsin (2) which are reported for the first time from this species. The structure elucidation of the isolated compounds was based on 1D and 2DNMR analysis and by the comparison with the published data. The lignans 1 and 2 showed significant inhi...

Alcohollc extract of C. mulnd resin (guggal) and one pure steroid isolated from this extract, when administered orally at a dose of 25-50 mgjkg body weight, reduced the serum cholesterol level in normal and triton-induced byperUpemlc rats and cholesterol-fed byperlipemIc rabbits. Both guggal extract and the steroid showed only slight inhibition of cholesterol biosynthesIs 85 compared to p_chlor...