Abnormalities in osmotic fragility have been observed in hereditary spherocytosis, hereditary elliptocytosis, pyruvate kinase deficiency, thalassaemia and iron-deficient red cells (1). Harris et al have reported a decrease in osmotic fragility of the red cells of sickle cell anaemia patients from Africa (2). The Indian patients are genetically and clinically different from the African patients ...

A precise and highly reproducible method for analyzing the osmotic fragility of erythrocytes with a minute amount of blood (less than 10 mul) is described. The osmotic fragility curves are recorded with a coil planet centrifuge with accessories and a scanning photodensitometer. The recorded curves are transcribed by a DuPont Curve Resolver and their components are analyzed. Normal fragility cur...

This paper represents the first effort in seismic fragility analysis of a structure using a structural analysis model developed on the basis of measured vibration data. An instrumented highway bridge is used to demonstrate the analysis procedure involving measuring ambient vibration, identifying modal parameters from the measured data, updating a preliminary FE model (obtained from structural d...

Elastic-plastic behavior of a beam made of functionally graded material is investigated in this work‎. ‎The beam is subjected to the constant axial and bending loads and the critical values of these loads for yield‎, ‎collapse and elastic-plastic conditions are obtained‎. ‎The variation of elastic modulus and yield strength through the height of the beam is determined with an exponential rule‎....

After learning from several devastating earthquakes in China in recent years, stricter design criteria have been introduced in the current Chinese seismic design code. To investigate the reliability of the current seismic design code, seismic fragility analyses were performed for 45 10-story reinforced concrete (RC) frame-shear wall structures designed according to the current Chinese seismic d...

Structural engineers, researchers, code committees, and regulatory bodies have become increasingly interested in performance-based design of structures, systems, and components (SSCs) in the past few years. This has been demonstrated by the publication of codes for the performance-based design of traditional buildings, and by publication of a consensus standard for evaluating the seismic perfor...

Why do starless cores appear more flattened than protostellar cores? ABSTRACT We evaluate the intrinsic three dimensional shapes of molecular cores, by analysing their projected shapes. We use the recent catalogue of molecular line observations of Jijina et al. and model the data by the method originally devised for elliptical galaxies. Our analysis broadly supports the conclusion of Jones et a...