BACKGROUND: Tumours form an integral part of disease process affecting the CNS and constitute a major part of all intracranial space occupying lesions. AIM: To study the histological findings of CNS tumors and to classify them according to WHO classification. MATERIALS AND METHODS: This is a five year study in which all the specimens of tumors of brain and spinal cord received in the department...

OBJECTIVE The aim of this report is to provide accurate nationwide epidemiologic data on primary brain and central nervous system (CNS) tumors in Republic of Korea. In 2010, we had reported first nationwide epidemiologic data on primary brain tumors diagnosed in 2005. In this report, we updated the data by analyzing primary brain and CNS tumors diagnosed in 2010 using the data from national can...

Tumors of the Central nervous System (CNS) are a spectrum neoplasms that range from benign lesions to highly malignant and aggressive lesions. Despite multimodal treatment approaches, morbidity mortality high with dismal survival outcomes in these tumors. Moreover, non-specificity conventional treatments substantiates rationale for precise therapeutic strategies selectively target infiltrating ...

Meningiomas are common, benign tumors found in the dural layers of central nervous system (CNS) that often incidentally. 18F-fluciclovine is an amino acid radiotracer used to monitor recurrence prostate cancer due its high uptake cells. This case report outlines a patient with retinoblastoma tumor suppressor gene (RB1) mutation and metastasis bone incidentally noted have enhancing, extra-axial ...

Cancer immunotherapy is the use of the immune system to reject cancers. The main premise is to harness the patient's immune system to attack the malignant tumor cells. This area of research has made tremendous progresses, and the United States Food and Drug Administration recently approved a vaccine for prostate cancers as the first approval for vaccines against non-viral cancers (Kantoff et al...

Abstract Background Central nervous system (CNS) cancer is the 10 th leading cause of cancer-associated deaths for adults, but in pediatric patients and young adults. The variety complexity histologic subtypes can lead to diagnostic errors. DNA methylation an epigenetic modification that provides a tumor-type specific signature be used diagnosis. Methods We performed prospective study using ana...

Ataxia can be classified according to the onset into episodic, acute, intermittent and chronic ataxia. Acute ataxia in children is caused by CNS tumors, trauma, CNS infection, toxins, metabolic causes or stroke. Recurrent ataxia can be due to metabolic causes, seizures, basilar artery migraine or toxins. Chronic ataxia is usually the result of hereditary ataxia, CNS tumors, congenital anomalies...