In this work, an eco-friendly procedure for the preparation of 2,3-dihydroquinazoline-4(1H)-ones was developed by condensation reaction of benzylic and heterocyclic aldehydes with 2-aminobenzamide in the presence of catalytic amounts of cyanuric chloride (2,4,6-trichloro-1,3,5-triazin) as an available and inexpensive organo-catalyst under aqueous media as a green conditions. The new co...

2,4,6-triisopropylstryrene was synthesized in a single step via the witting reaction from the corresponding aldehyde. the reaction of three styrene's derivatives, 2,6-dimethylstyrene, 2,4,6-trimethylstyrene, and 2,4,6- triisopropylstyrene with 4-methyl-l,2,4-triazoline-3,5-dion(m etd) was investigated. these reactions are instantaneous at room temperature and lead to the formation of 2: 1 ...

Abstract Background Reproducible, high-quality surgery is a key point in the management of cancer patients. Quality indicators for surgical treatment melanoma has been presented with benchmarks but data on morbidity are still limited. This study presents quality after non-metastatic skin an Italian registry. Methods Data were extracted from Central National Melanoma Registry (CNMR) promoted by ...

An efficient synthesis of chromenylphenylpropanone derivatives as warfarine-like analogues was developed by the Michael addition of 4-hydroxycoumarin to α,β-unsaturated compounds in the presence of polyvinylpolypyrrolidone supported antimony(III) chloride (PVPP-SbCl3) as a new polymeric Lewis acid catalyst in chloroform at reflux conditions without formation of 2,4-...

poly methyl methacrylate (pmma) is the most common material used in prosthodontics. several studies indicate a breakdown of the number of very high resin bases after 2 to 3 years to avoid breaking bass and several attempts have been made, such as altering the chemical structure of resin by adding causes cross linking or copolymerization. the innovative method for improving the physical properti...

Poly methyl methacrylate (PMMA) is the most common material used in Prosthodontics. Several studies indicate a breakdown of the number of very high resin bases after 2 to 3 years to avoid breaking bass and several attempts have been made, such as altering the chemical structure of resin by adding causes cross linking or copolymerization. The innovative method for improving the physical properti...

All reactions were carried out with magnetic stirring under an atmosphere of argon in oven-dried glassware. Methanol was purchased from Sigma-Aldrich and stored in an anhydrous atmosphere. Sodium acetate was purchased from Aldrich and stored under anhydrous atmosphere. H NMR spectra were recorded on Varian 400 MHz spectrometer at ambient temperature or a Bruker Avance III 500 (500 MHz). Data is...

Oleanan derivative compound namely 3-acetyl-12-oleanen-28-oic acid, has been isolated from n-hexane fraction of the bark M. umbellate (Houtt) Stapf var. degrabrata The molecular structure was determined by IR spectroscopy, NMR 1D and 2D (H-NMR, CNMR, DEPT, COSY, HMQC and HMBC). The results of test bioactivity to hexane, chloroform, ethyl acetic, methanol extracts and compound 1 mentioned above ...

A new quinoxaline-substituted vicinal dioxime ligand containing bis(12-diazacrown-4) units (H2L) was synthesized by the reaction of cyanogen di-N-oxide with compound 4. Mononuclear Ni and Cu complexes with a metal: ligand ratio of 1:2 for H2L and a trinuclear Cu II complex were also synthesized. The mononuclear Cu species coordinated to two Cu ions through the deprotonated oximate oxygens to yi...

In order to develop new anticoagulants as the potential alternatives of heparin, microcrystalline cellulose (MCC) was used as a starting polymer and chlorosulfonic acid in N,N-dimethylformamide (ClSO 3 H-DMF) was used as a sulfation agent for the semi-synthesis of cellulose sulfate sodium, coded as Na-MCS. IR spectra showed that the sulfate group was introduced by the reaction. The sulfation de...