Four subclinical mastitis diagnostic tests (the UdderCheck® test [a lactate dehydrogenasebased test], the California Mastitis Test [CMT], the Draminski® test [a conductivity-based test] and the PortaSCC® test [a portable somatic cell count-based test]) were compared in a study comprising crossbreed dairy cows (n = 30) during September and October 2015. Sensitivity and specificity of the CMT, Dr...

A total of 335 quarter milk samples from crossbred dairy cows were subjected to California mastitis (CMT), sodium lauryl sulphate (SLST), and somatic cell count (SCC) tests. CMT positive milk samples were 227, while 108 samples were CMT negative. Milk samples positive by SLST and SCC were 261 and 180 respectively. The CMT positive samples were subjected to cultural isolation (gold standard test...

California mastitis test (CMT), direct leukocytes counts and bacteriological examination were performed on 630 milk samples from apparently healthy mammary glands of dairy goats comprising a mixed population of German Alpine, Toggenberg, Saanen and Galla crosses to find the prevalence of subclinical mastitis. The prevalence of subclinical mastitis was 9.8% according to CMT, 9.7% according to di...

Background: Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral neuropathy and is associated with debilitating lower limb impairments and activity limitations. These impairments and activity limitations are potentially amendable to the prescription of orthoses, yet there is no universal, literature-based consensus to inform the decision making process of whether or not ort...

Charcot-Marie-Tooth (CMT) neuropathies comprise a group of monogenic disorders affecting the peripheral nervous system. CMT is characterized by a clinically and genetically heterogeneous group of neuropathies, involving all types of Mendelian inheritance patterns. Over 1,000 different mutations have been discovered in 80 disease-associated genes. Genetic research of CMT has pioneered the discov...

Objective: Charcot-Marie Tooth (CMT) disease is the most common inherited neurological disorder of lower motor neurons, and manifests with lower extremity weakness and sensory defects. Musculoskeletal imaging findings in CMT include cavovarus foot alignment and peripheral muscle atrophy. There is a lack of literature describing the imaging appearance of peripheral nerves in patients with CMT. T...

Galectin-3 is a glycan-binding protein that mediates cell-cell and/or cell-extracellular matrix (ECM) interactions. Although galectin-3 is implicated in the progression of various types of cancers, the mechanisms by which galectin-3 enhances metastasis remain unclear. In order to elucidate the role of galectin-3 in the complex multistage process of cancer metastasis, we examined galectin-3 and ...

Background Charcot-Marie-Tooth disease (CMT) is the most common hereditary peripheral neuropathy, with an incidence of 1 in 2,500 [1]. CMT is characterised by the progressive weakening of the distal muscles and sensory loss of the limbs, particularly around the foot and ankle resulting in balance, walking impairments, cavus foot deformity and lateral instability [2,3]. Clinical anecdotes sugges...

Toxin or medication-induced worsening of preexisting peripheral neuropathy is a generally accepted but not well-studied phenomenon in humans. Drug-induced exacerbation of Charcot Marie Tooth disease (CMT) neuropathy is a common concern; a list of potential drugs to avoid is maintained by the CMT Association but with limited direct evidence or advice on relative risk. An extensive literature sea...