California mastitis test (CMT), direct leukocytes counts and bacteriological examination were performed on 630 milk samples from apparently healthy mammary glands of dairy goats comprising a mixed population of German Alpine, Toggenberg, Saanen and Galla crosses to find the prevalence of subclinical mastitis. The prevalence of subclinical mastitis was 9.8% according to CMT, 9.7% according to di...

Background: Charcot–Marie–Tooth disease (CMT) is the most common inherited peripheral neuropathy and is associated with debilitating lower limb impairments and activity limitations. These impairments and activity limitations are potentially amendable to the prescription of orthoses, yet there is no universal, literature-based consensus to inform the decision making process of whether or not ort...

Charcot-Marie-Tooth (CMT) neuropathies comprise a group of monogenic disorders affecting the peripheral nervous system. CMT is characterized by a clinically and genetically heterogeneous group of neuropathies, involving all types of Mendelian inheritance patterns. Over 1,000 different mutations have been discovered in 80 disease-associated genes. Genetic research of CMT has pioneered the discov...

Objective: Charcot-Marie Tooth (CMT) disease is the most common inherited neurological disorder of lower motor neurons, and manifests with lower extremity weakness and sensory defects. Musculoskeletal imaging findings in CMT include cavovarus foot alignment and peripheral muscle atrophy. There is a lack of literature describing the imaging appearance of peripheral nerves in patients with CMT. T...

Galectin-3 is a glycan-binding protein that mediates cell-cell and/or cell-extracellular matrix (ECM) interactions. Although galectin-3 is implicated in the progression of various types of cancers, the mechanisms by which galectin-3 enhances metastasis remain unclear. In order to elucidate the role of galectin-3 in the complex multistage process of cancer metastasis, we examined galectin-3 and ...

Background Charcot-Marie-Tooth disease (CMT) is the most common hereditary peripheral neuropathy, with an incidence of 1 in 2,500 [1]. CMT is characterised by the progressive weakening of the distal muscles and sensory loss of the limbs, particularly around the foot and ankle resulting in balance, walking impairments, cavus foot deformity and lateral instability [2,3]. Clinical anecdotes sugges...

Toxin or medication-induced worsening of preexisting peripheral neuropathy is a generally accepted but not well-studied phenomenon in humans. Drug-induced exacerbation of Charcot Marie Tooth disease (CMT) neuropathy is a common concern; a list of potential drugs to avoid is maintained by the CMT Association but with limited direct evidence or advice on relative risk. An extensive literature sea...

OBJECTIVE To investigate the effect of maternal Charcot-Marie-Tooth disease (CMT) on pregnancy and delivery. METHODS Data from the Medical Birth Registry of Norway 1967 to 2002 were surveyed. This registry has compulsory notification of all births. One hundred eight births by mothers with CMT were identified. The reference group consisted of all 2.1 million births by mothers without CMT. RE...

Purpose To investigate the correlation between visual acuity and central macular thickness (CMT) and choroidal thickness (CCT) in patients with wet age-related macular degeneration (AMD). Methods In this retrospective analysis, 14 eyes that received >10 ranibizumab injections (based on pro re nata [PRN] regimen) and maintained initial visual acuity gain were analyzed. The following 5 paramete...