We identified primary cilia and centrosomes in cultured human umbilical vein endothelial cells (HUVEC) by antibodies to acetyl-alpha-tubulin and capillary morphogenesis gene-1 product (CMG-1), a human homologue of the intraflagellar transport (IFT) protein IFT-71 in Chlamydomonas. CMG-1 was present in particles along primary cilia of HUVEC at interphase and around the oldest basal body/centriol...

In this article, we review our efforts to continuously tune mechanical and thermal properties in multilayer chemically modified graphene (CMG) films. An alteration of the graphene lattice by functional groups, by defects created during reduction, or by defect re-crystallization is used to control CMG mechanical and thermal properties. We attribute a notable increase in Young’s modulus and film ...

Applications of Enhanced Oil Recovery (EOR) are highly required and needed in Sudan to keep oil supply at stable levels. ”FUL” Oilfield has shallow reservoir affected by big boundary bottom water drive with high crude viscosity. This research, through a comprehensive analysis the current producing wells, perforation intervals, CO2 temperature analysis, steam parameters optimization which using ...

Establishing "large-contact-area" interfaces of sensitive nanostructures with microbes and mammalian cells will lead to the development of valuable tools and devices for biodiagnostics and biomedicine. Chemically modified graphene (CMG) nanostructures with their microscale area, sensitive electrical properties, and modifiable chemical functionality are excellent candidates for such biodevices a...

DNA polymerase epsilon (Pol ε) synthesizes the leading strands, following the CMG (Cdc45, Mcm2-7, and GINS [Go-Ichi-Nii-San]) helicase that translocates on the leading-strand template at eukaryotic replication forks. Although Pol ε is essential for the viability of fission and budding yeasts, the N-terminal polymerase domain of the catalytic subunit, Cdc20/Pol2, is dispensable for viability, le...

This study was conducted to explore an accurate site identification technique using a geographic information system (GIS) and geo-temperature (gT) for locating suitable sites for growing cultivated mountain ginseng (CMG; Panax ginseng), which is highly sensitive to the environmental conditions in which it grows. The study site was Jinan-gun, South Korea. The spatial resolution for geographic da...

We present a cancer nanomedicine based on acidic pH targeted gold nanorods designed for multispectral optoacoustic tomography (MSOT). We have designed gold nanorods coated with mesoporous silica and subsequently capped with chitosan (CMGs). We have conjugated pH-sensitive variant 7 pHLIP peptide to the CMGs (V7-CMG) to provide targeting specificity to the acidic tumor microenvironment. In vitro...

In this work we present the predictions of a modified version of the “two-infall model” (Chiappini et al. 1997 CMG) for the evolution of He, He and D in the solar vicinity, as well as their distributions along the Galactic disk. In particular, we show that when allowing for extramixing process in low mass stars (M< 2.5 M⊙), as predicted by Charbonnel and do Nascimento (1998), a long standing pr...

Adaptor proteins, by bringing together kinases and other effectors, form a submembrane scaffold of signaling molecules. One such adaptor, Drosophila Camguk (CMG), is a member of the membrane-associated guanylate kinase family and associates with calciumand calmodulin-dependent protein kinase II (CaMKII). This week, Marble et al. describe a signaling complex including CMG, CaMKII, and the Ether-...

AIMS Cells derived from the stroma vascular fraction (SVF) of mouse adipose tissue can spontaneously give rise to rare, functional, cardiac-like cells in vitro. This study aimed to improve the production of adipose-derived cardiomyogenic cells (AD-CMG), to characterize them and to assess their cardiac fate and functional outcomes after their administration in a mouse model of acute myocardial i...