Identifying which ligands might bind to a protein before crystallization trials could provide a significant saving in time and resources. LigSearch, a web server aimed at predicting ligands that might bind to and stabilize a given protein, has been developed. Using a protein sequence and/or structure, the system searches against a variety of databases, combining available knowledge, and provide...

This paper presents a Page Rank based prefetching technique for accesses to web page clusters. The approach uses the link structure of a requested page to determine the “most important” linked pages and to identify the page(s) to be prefetched. The underlying premise of our approach is that in the case of cluster accesses, the next pages requested by users of the web server are typically based ...

The binding of transcription factors to specific regulatory sequence elements is a primary mechanism for controlling gene transcription. Eukaryotic genes are often regulated by several transcription factors whose binding sites are tightly clustered and form cis-regulatory modules. In this paper, we present a web server, CREME, for identifying and visualizing cis-regulatory modules in the promot...

UNLABELLED New techniques in sample preparation allow high throughput analysis of samples on the transcriptional as well as on the metabolic level. We present a service accessible via the web that allows the analysis of integrated data sets that combine gene-expression data and metabolic data. After uploading, data sets can be normalized, clustered by various methods and results can be graphica...