An efficient approach for the synthesis of monosubstituted aromatic compounds relying on a ring-closing metathesis followed by spontaneous 1,2-elimination is presented. The efficiency late-stage functionalization highlighted in various solvents (up to 920 TON). This compatible with strained cycles and other multiple bonds substrate.

M yosin takes both the high road and the low road to close wounds, as revealed by Tamada et al. on page 27. The motor is found in a high contractile actin ring and in bottomdwelling membrane protrusions. Wound closure requires a cable of actin and myosin in the cells that border the wound. The contraction of this cable draws these border cells together to fi ll in the hole. In fl ies, however, ...

In the title solvated benzimidazole compound, C(20)H(15)N(3)O(2)·C(2)H(6)OS, both the benzimidazole fused-ring system and the complete dimethyl sulfoxide solvent mol-ecule are disordered over two sets of sites, in 0.750 (5):0.250 (5) and 0.882 (4):0.118 (4) ratios, respectively. The conformation of the pyrimidine ring is close to a half-chair for the major disorder component, whereas for the mi...

In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.87 (9)°]. However, the phenyl ring in the 5-position forms a dihedral angle of 72.31 (9)°. The hy-...

Stationary phase cultures of Candida albicans inoculated into fresh medium at 37 degrees C synchronously from buds at pH 4.5 and mycelia at pH 6.5. During bud formation, a filament ring forms just under the plasma membrane at the mother cell-bud junction at roughly the time of evagination. A filament ring also forms in mycelium-forming cells, but it appears later than in a budding cell and it i...

In the title compound, C(18)H(11)Br(2)ClO(3), an intra-molecular O-H⋯O=C hydrogen bond occurs, forming a six-membered ring. The naphthalene ring system and the benzene ring make a dihedral angle of 57.36 (9)°. The central carbonyl C-(C=O)-C group is twisted away from the naphthalene ring system and the benzene ring by 18.61 (15) and 26.25 (16)°, respectively. In the crystal structure, two inter...

let r be an associative ring with unity. an element a in r is said to be r-clean if a = e+r, where e is an idempotent and r is a regular (von neumann) element in r. if every element of r is r-clean, then r is called an r-clean ring. in this paper, we prove that the concepts of clean ring and r-clean ring are equivalent for abelian rings. further we prove that if 0 and 1 are the only idempotents...