Since the identification of cancer stem cells (CSCs) a new understanding of tumor occurrence and development has evolved. According to the stem cell (SC) theory, colorectal carcinoma (CRC) SCs may be derived from mutations in normal intestinal cells. CSCs can be defined by their cell of origin (SCs or early progenitor cells). Thus, through a shared stem cell marker between CSCs and SCs, it is p...

BACKGROUND The purpose of this study was to investigate the correlation between B-type Raf (BRAF) kinase mutation and clinicopathological features of follicular variant of papillary thyroid carcinoma (PTC). METHODS Eighty-four patients with pathologically confirmed follicular variant of PTC, who underwent a preoperative BRAF(V600E) study, were analyzed. Clinicopathological parameters and ultr...

background: primary gastric lymphoma (pgl) is an uncommon malignancy with various histological subtypes and treatment outcomes. the aim of this study was to investigate the potential prognostic factors and clinicopathological characteristics of iranian patients with pgl. methods: the clinicopathological characteristics of 60 patients with pgl were retrospectively reviewed from 2001 to 2012. the...

My intention in this paper is to outline and motivate a novel theory of syntactic bootstrapping, Exemplar-Based Phonological Bootstrapping (EBPB), based on Stochastic Tree-Substitution Grammar. Because I have outlined the basic structure of STSG in other places for assessed work on this degree, I will not recapitulate that work in the body of the present paper, but will instead quote it in full...

Objective(s):Previous studies demonstrate that changes in pre-mRNA splicing play a significant role in human disease development. Furthermore, many cancer-associated genes are regulated by alternative splicing. There are mounting evidences that splice variants which express predominantly in tumors, have clear diagnostic value and may provide potential drug targets. Located on the X chromosome, ...

Database queries within a component framework usually take the form of a string passed to an operation in a component’s interface. The interface operation accepts a value of type string as an actual parameter and implements the necessary support to resolve the query. In such an approach, a component’s interface does not explicitly state the queries supported by that component. In this paper, we...

Soft glassy materials exhibit the so-called glassy transition which means that the behavior of the model at low shear rate changes when a certain parameter (which we call the glass parameter) crosses a critical value. This behavior goes from a Newtonian behavior to a HerschelBulkley behavior through a power-law-type behavior at the transition point. In a previous paper we rigorously proved that...

Combined logics have recently deserved much attention. In this paper we develop a detailed study of a form of combination that generalises the temporalisation construction proposed in 9]. It consists of replacing an atomic part (formal parameter) of one (parameterised) logic by another (actual parameter) logic. We provide a categorial char-acterisation of parameterisation and illustrate it with...