b a ckground: quorum-sensing systems regulate expression of several virulence factors in pseudomonas aeruginosa . this study investigated the relation between expression of the las quorum-sensing system and expression of mexy and ampc in35 clinical isolates of p. aeruginosa . m e t hods: antibiotic susceptibility was determined by the disc diffusion method according to the clinical and laborato...

conclusions the levels of resistance to ceftazidime were remarkably variable among ctx-mproducers. this study provides further evidences of the global dissemination of ctx-m type esbls and emphasized on the need for their epidemiological monitoring. results in phenotypic confirmatory test, 154 (44%) out of 350 clinical isolates were esbl positive. using molecular assay, 154 strains potentially ...

Objective(s): Integrons, as a potential element in the distribution and maintenance of drug resistance, have thoroughly been established. It is known that the high prevalence of integrons in multidrug-resistant (MDR) clinical isolates has become a serious public health concern. The objective of the present study was to determine the frequency of different classes of integrons in clinical isolat...

Objective(s) Different types of extended spectrum beta-lactamases (ESBLs) are encountered in the clinical settings worldwide. There are a few studies regarding the prevalence of ESBL genes among Klebsiella pneumoniae isolates at Tehran especially those of blaPER and blaCTX. The aim of this study was to determine the prevalence of blaSHV, blaTEM ,blaPER and blaCTX genes among clinical K. pneumo...

Background & Aims: One of the main causes of nosocomial infection is pseudomonas aeruginosa and carbapenems is one of the most important classes of antibiotics used in the treatment of infections caused by this bacteria. Metallo-beta-lactamase (MBL) production is one of the most important mechanisms of resistance to carbapenems and their increased prevalence is a serious threat to treatment of ...