number of studies of genetic and molecular effects on rrhythmogenesis are noteworthy. ong QT syndrome (LQTS). Despite the great advances n our understanding of the role of channel disorders as auses for the LQTS, at present in at least 25% of these atients no genetic defect has been established. The idenified mutant genes are responsible for coding either the lpha (membrane spanning) or rarely ...

Personalized cardiac electrophysiology simulations have demonstrated great potential to study arrhythmias and help in therapy planning of radio-frequency ablation. Its application analyze vulnerability ventricular tachycardia sudden death infarcted patients has been recently explored. However, the detailed multi-scale biophysical used these studies are very demanding terms memory computational ...

CARDIOVASCULAR FLASHLIGHT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . doi:10.1093/eurheartj/ehv...

IN THE CONTEXT of history scientists often share the fate of artists, for the final judgment of their work is subject to the whims of later generations. Even a great scientist may fade into obscurity as later investigators incorporate his ideas into their own and forget their origin. Such a fate seems to have befallen John Scott Burdon-Sanderson. Working in the last two decades of the nineteent...