INTRODUCTION The high prevalence of Klebsiella pneumoniae infections is related to the ability of K. pneumoniae to acquire and disseminate exogenous genes associated with mobile elements, such as R plasmids, transposons and integrons. This study investigated the presence of class 1 integrons in clinical and microbiota isolates of K. pneumoniae belonging to different phylogenetic groups and corr...

conclusions: our findings suggest the possible co-carriage of some blashv genes and aris on the same plasmids harboring the mdr genes. possible role of integrons in dissemination of esbl-encoding blashv genes among esbl-producing k. pneumoniae nosocomial isolates may be inferred. background: some genetic and phenotypic variables are associated among distinct microbial populations. objectives: t...

It is believed that high antibiotic consumption and horizontal transfer of resistance genes are two major causes of antibiotic resistance in bacteria. To confirm or reject this belief, we studied the role of drug administration in antimicrobial resistance (AMR), prevalence of Class I and II integrons and integron-mediated resistance in Escherichia coli isolated from human and animal specimens. ...

Integrons are genetic elements that contribute to lateral gene transfer in bacteria as a consequence of possessing a site-specific recombination system. This system facilitates the spread of genes when they are part of mobile cassettes. Most integrons are contained within chromosomes and are confined to specific bacterial lineages. However, this is not the case for class 1 integrons, which were...

conclusions the study revealed a high prevalence of multi-drug resistance (mdr), class 1 integron, sccmec type iii, and spa type t030 amongst mrsa associated with burn wounds in an iranian hospital. the existence of sccmec type iii in burn patients emphasizes the nosocomial origin of these strains. objectives the aim of this study was to determine the distribution and molecular types of mrsa in...

Integrons are associated with a variety of gene cassettes, which confer resistance to multiple classes of antibacterial drugs. In this study we tested the frequency of class 1 and 2 integrons among multidrug-resistant Acinetobacter baumannii (MDRAB) clinical isolates. One hundred clinical isolates of A. baumannii were screened for carriage of class 1 and 2 integrons by PCR method. Results showe...

Integrons are genetic elements first described at the end of the 1980s. Although most integrons were initially described in human clinical isolates, they have now been identified in many non-clinical environments, such as water and soil. Integrons are present in ≈10% of the sequenced bacterial genomes and are frequently linked to mobile genetic elements (MGEs); particularly the class 1 integron...