A total of 154 patients admitted to an infectious diseases unit were included in a year's prospective survey of sporadic diarrhoeal disease. Stools from 19 of them yielded Clostridium difficile, generally on more than one occasion. Twelve of these patients were assessed as having a severe or moderately severe gastrointestinal illness: Cl difficile was the only pathogen isolated from 10 of them,...

Based on the generalized gradient approximation of density functional theory, geometric structure and electronic properties intrinsic Ti3C2 Cu-, Pt-, Co-, Si-, F-, Cl- or Br-doped are optimized, adsorption process HCHO surface doped is calculated. The effects energy, stability, DOS doping bond length were discussed. results show that energy crystal plane at top site strongest, −7.58 eV. optimal...

the late eocene-early oligocene sarnowsar granitic rocks and many dacitic to rhyolitic dykesintruded in metamorphosed and metasomatized shale, sandstone, calcite and dolomite marbles andvolcaniclastic and pyroclastic rocks. as a result several million tons of iron ores formed within carbonaterocks in the sangan area. the sarnowsar granitic rocks are mainly granite to granodiorite, metaluminous,...

The Yellow River has played an indispensable role in supporting Chinese civilization because it provides water resources and rich soil for agriculture. This study analyzes the major ions isotopic ratios of hydrogen (δD), oxygen (δ18O), carbon (14C) groundwater samples to identify sources recharge impact on Changqing-Xiaolipu karst aquifer. ion/Cl− generally follow mixing line between southern m...

This study examined relationships between some acoustic response properties of 'cluster' recordings (CL) and their constituent single cells (SU) in the auditory cortex obtained from 22 clusters comprised of 63 responsive single units mainly in the anterior tonotopic field of the waking guinea pig. Response parameters included characteristic frequency (CF), threshold (Th) at CF, bandwidth 10 (BW...

In vitro models based on primary human hepatocytes (PHH) have been advanced for clearance (CL) prediction of metabolically stable compounds, representing state-of-the-art assay systems for drug discovery and development. Yet, limited cell availability and large interindividual variability of metabolic profiles remain shortcomings of PHH. Upcyte human hepatocytes (UHH) represent a novel hepatic ...

Mammalian CLC proteins comprise both Cl- channels and Cl-/H+ antiporters that carry out fundamental physiological tasks by transporting Cl- across plasma membrane and intracellular compartments. The NO3- over Cl- preference of a plant CLC transporter has been pinpointed to a conserved serine residue located at Scen and it is generally assumed that the other two binding sites of CLCs, Sext and S...

BACKGROUND Children with a Cleft Lip and/or Palate (CL/P) have been reported to have poorer oral health than those without the condition. The consequences for these children can be particularly problematic due to implications for future treatments. Tooth brushing is an important behaviour contributing to children's oral health, but is under researched in the CL/P population. The aim of the stud...