OBJECTIVE Electrocardiography (ECG) may be a practical guiding tool for prognostic infarct sizing in ST elevation acute myocardial infarction (STEAMI). In this study, we sought to find a relation between the infarct size and the change in the QRS axis after thrombolytic therapy. MATERIALS AND METHODS Patients with STEAMI who received thrombolytic therapy were selected retrospectively. The mea...

Starburst dendrimers are novel, water-soluble polymeric materials, with a well-defined composition and structure. In our application, we used dendrimers composed of poly(amidoamine) groups to which we coupled several specific antibodies, to investigate potential formats based on radial partition immunoassay. The coupled antibodies have retained their stability and immunological binding after co...

Results Mean baseline BNP, TnI and CK-MB levels were 304.01 pg/ml, 0.03 ng/ml and 0.99 ng/ml. BNP initially decreased within 6 hours of surgery, and peaked at 24 hours; TnI and CKMB showed an early rise, with declining trends by 24 hrs. Peak BNP levels occurred in 90% patients by 24-48 hrs, while for TnI and CKMB this occurred in only 15-30%. Mean delta (peak-baseline) BNP, TnI, CKMB was 660.1p...

Objective: To assess the rise in CKMB and Myoglobin levels associated factors non-cardiac patients of ischemic stroke presenting to Emergency Department a Tertiary Care Hospital.
 Study Design: Cross-sectional study.
 Place Duration Study: Medicine, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Dec 2020 May 2021.
 Methodology: A total 150 with diagnosed by cons...

Background: Creatine kinase MB (CK-MB), which exists mainly in the cytoplasm of myocardial cells, is currently accepted as an indicator and has high sensitivity specificity for diagnosis injury. Objective: This study was aimed to estimate serum creatine (CK-MB) levels after asphyxia-induced injury neonates. Patients methods: 40 neonates were included this divided into 20 cases with perinatal h...

conclusions selenium can alleviate i/r injury in short time. further well-planned trials are needed to find the optimized administration method to achieve the most beneficial effects to the patients. background in patients with coronary artery stenosis, coronary artery bypass graft surgery (cabg) is the most effective strategy to limit infarct size and improving outcomes. however, the rapid res...

Background: Isoproterenol, a β-adrenergic agonist, may induce myocardial infarction when used in high dosage rats. This study was conducted to evaluate the effect of ethanol extract Kleinhovia hospita leaves on cardiac biomarkers and structures rats induced by isoproterenol. Methods: Male (n=30) were assigned as normal controls or treatment groups. The groups received pretreatments, either plac...

BACKGROUND Many small, randomized, controlled trials have evaluated the effectiveness of blood as compared with crystalloid cardioplegia for myocardial protection during cardiac surgery. Blood cardioplegia provides a closer approximation to normal physiology, which may translate into measurable clinical benefits. This meta-analysis describes the effectiveness of blood cardioplegia in lowering a...

Agroclavine is a natural, clavine type of ergot alkaloid with D1 dopamine and a-adrenoceptor agonistic properties. We showed previously that in vitro agroclavine enhances natural killer (NK) cell activity, increases interleukin-2 and interferon-gamma production and prolongs the survival time of tumor-bearing mice. The aim of this study was 1) to test the effect of agroclavine on NK activity in ...

Background Although the rapid reperfusion by coronary artery bypass graft (CABG) surgery has significant success and it can cause decrease in mortality and morbidity rate, but this reperfusion paradoxically can cause ionic and metabolic damage that lead to myocardial damage and myocytes death. We examined whether perioperative exogenous erythropoietin (EPO) can reduce myocardial damage by reduc...