Background and Objective: The cost of substrate represents a significant percentage the total biosynthesis citric acid. There is need to continue searching for better cheap underutilize starchy raw material acid biosynthesis. Therefore, objective this research was biologically synthesis in submerged fermentation Aspergillus niger using wild Dioscorea esculenta (wild yam) tubers.
 Methodolo...

The aim of this study is to optimize the production of Baker’s yeast, Citric acid, Ethanol and α-amylase using dates of low market value as the basal fermentation medium. The results of this study showed that the optimal Baker’s yeast production was obtained with a dilution rate of 0.22 h-1. Also, the use of ammonium phosphate provides better biomass yields compared to urea. As for the Ethanol ...

In the present investigation, we report that statistical design and optimization of significant variables for the microbial production of citric acid from sucrose in presence of filamentous fungi A. niger NCIM 705. Various combinations of experiments were designed with Central Composite Design (CCD) of Response Surface Methodology (RSM) for the production of citric acid as a function of six var...

Owing to new biotechnological production units mostly located in China, global supply of citric acid in the course of the last two decades rose from less than 0.5 to more than 2 million tonnes becoming the single largest chemical obtained via biomass fermentation and the most widely employed organic acid. Critically reviewing selected research achievements and production trends, we identify the...

Citric acid was produced with free and k-carrageenan-entrapped cells of the yeast Yarrowia lipolytica in single and repeated batch-shake-flask fermentations on glycerol-based media. Simultaneous solubilization of hydroxyapatite of animal bone origin (HABO) was tested in all experiments. The highest citric acid production by free yeast cells of 20.4 g/L and 18.7 g/L was reached after 96 h of fer...

BACKGROUND Agricultural waste is as an alternative low-cost carbon source or beneficial additives which catch most people's eyes. In addition, methanol and sweet potato vine hydrolysate (SVH) have been reported as the efficient enhancers of fermentation according to some reports. The objective of the present study was to confirm SVH as an efficient additive in CA production and explore the syne...

BACKGROUND Unlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica, an oleaginous yeast, is recognized for its potential to produce single cell oils and citric acid from different feedstocks. These versatilities of Y. lipolytica with regards to substrate utilization make it an attractive host for biorefinery appl...

A solid state fermentation method was used to utilize wheat straw as substrates for citric acid production by using Aspergillus niger ATCC 9142. The Plackett Burman design (PBD) of experiments was used to test the relative importance of the variables affecting production such as moisture content, age of spore, inoculum size, initial pH of substrate, methanol conce...

There has been a steady increase in the consumption of citric acid during the past 25 years. An estimate by Cochrane (1948) places annual manufacture at approximately 35 million pounds. Commercial production of citric acid is reputedly based on fermentation by Aspergillus niger of a suitable grade of beet syrup in shallow pans. A submerged process appears to be highly desirable, and many articl...

Anaerobic growth of Klebsiella aerogenes NCDO 711 (NCTC 418) on citrate was dependent on the presence of Na+ in the medium, and fermentation of citrate was mediated via the fermentation pathway enzymes, citrate lyase and a Na+-dependent oxalacetate decarboxylase. This confirms the previous findings on strain NCTC 418. Growth under aerobic conditions was independent of Na+. The mean generation t...