نتایج جستجو برای: cis
تعداد نتایج: 43071 فیلتر نتایج به سال:
Background: Cisplatin (CIS), an anticancer alkylating agent, induces DNA adducts and effectively cross links the DNA strands and so affects spermatozoa as a male reproductive tract toxicant. Materials and Methods: The present study investigated the cellular/biochemical mechanisms underlying possible protective effect of selenium nano-particles (Nano-Se) as an established strong antioxidant with...
Objective(s): Cisplatin (Cis) is an anticancer compound, which is used for the treatment of various cancers. Sumatriptan (Suma) is a selective agonist of 5-hydroxytryptamine 1B/1D (5HT1B/1D) receptor, which is prescribed for the management of migraine. It is well-established that Suma has anti-inflammatory and antioxidant properties. We have explored the protective effe...
Background: Testicular Carcinoma in situ (CIS), also known as intratubular germ cell neoplasia (ITGCN), is a pre-invasive precursor of testicular germ cell tumours (TCGTs), i.e seminomas and non-seminomas -the commonest cancer type of male adolescents and young adults- which can be diagnosed using a surgical biopsy. Infertility is one of the condition known to predispose to TGCT, but based on s...
Background: Many recent studies have examined potential risk factors of H. pylori gastritis to improve our understanding of the early events in gastric carcinogenesis. We evaluated the extent and topography of chronic gastritis in a high risk area for gastric cardia cancer and investigated the critical role of H.pylori, risk index and age in its pathogenesis. Materials and Methods: During a na...
Background: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic acid (9-cis-RA) and 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) can ameliorate oligodendrogenesis. We investigated whether they could increase oligodendrogenesis by inhibiting the Wnt and Notch signaling pathways.Methods: Co...
abstract introduction : conjugated linoleic acid (cla) has been shown to positively influence on calcium and bone metabolism in experimental animals and cell culture, but there are limited human data available. material and methods : this double-blind, placebo-controlled trial study was done on 76 healthy post-menopausal women (aged 55.1) which randomly assigned to receive daily four cla capsul...
Abstract Background: Most animal studies have shown that trans-10 and cis-12 isomers of Conjugated linoleic Acid, (CLA) tend to increase insulin resistance. But the effect of equal isomers of CLA (50:50 ratios of cis-9, trans-11: trans-10, cis-12 isomers) on lipid profiles, glucose, and insulin resistance and sensitivity in postmenopausal women is not clear. Methods: In the present study, ...
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